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[男性不育症的合理诊断与治疗]

[Rational diagnosis and treatment of male infertility].

作者信息

Kliesch S

机构信息

Department of Clinical and Surgical Andrology, Centre of Reproductive Medicine and Andrology, WHO Collaborating Center for Research in Male Fertility, Training Center of the European Academy of Andrology, University Clinics of Muenster, 48149, Münster, Deutschland.

出版信息

Urologe A. 2017 Sep;56(9):1116-1128. doi: 10.1007/s00120-017-0455-8.

DOI:10.1007/s00120-017-0455-8
PMID:28726058
Abstract

Male infertility can be diagnosed by evaluation of the (female and) male history with respect to risk factors, and includes scrotal sonography, hormone and semen measurements. In severe male factor infertility, genetic testing is indicated. Treatment options vary between preventive, medical or surgical strategies depending on the underlying diagnosis. Assisted reproductive techniques may be applied as a consequence of the couple's infertility profile.

摘要

男性不育可通过评估(男女)双方病史中的风险因素来诊断,包括阴囊超声检查、激素和精液检测。对于严重的男性因素不育,需进行基因检测。根据潜在诊断结果,治疗方案可分为预防性、药物性或手术性策略。根据夫妻的不育情况,可能会应用辅助生殖技术。

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Dtsch Arztebl Int. 2017 May 12;114(19):339-346. doi: 10.3238/arztebl.2017.0339.
2
Delayed treatment of undescended testes may promote hypogonadism and infertility.隐睾延迟治疗可能会导致性腺功能减退和不育。
Endocrine. 2017 Mar;55(3):914-924. doi: 10.1007/s12020-016-1178-0. Epub 2017 Jan 9.
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Feasibility and Efficacy of a Urologic Profession Campaign on Cryptorchidism Using Internet and Social Media.一项利用互联网和社交媒体开展的关于隐睾症的泌尿外科专业宣传活动的可行性与效果
Urol Int. 2017;98(4):478-482. doi: 10.1159/000449257. Epub 2016 Nov 3.
4
Clinical, genetic, biochemical, and testicular biopsy findings among 1,213 men evaluated for infertility.1213 名不孕男性的临床、遗传、生化和睾丸活检结果。
Fertil Steril. 2017 Jan;107(1):74-82.e7. doi: 10.1016/j.fertnstert.2016.09.015. Epub 2016 Oct 25.
5
Testicular growth and spermatogenesis: new goals for pubertal hormone replacement in boys with hypogonadotropic hypogonadism? -a multicentre prospective study of hCG/rFSH treatment outcomes during adolescence.睾丸生长与精子发生:性腺功能减退性性腺功能低下男孩青春期激素替代治疗的新目标?——一项关于青春期hCG/rFSH治疗结果的多中心前瞻性研究
Clin Endocrinol (Oxf). 2017 Jan;86(1):75-87. doi: 10.1111/cen.13164. Epub 2016 Sep 7.
6
[Androprotect and prospects for fertility treatment].[雄激素保护与生育治疗前景]
Urologe A. 2016 Jul;55(7):898-903. doi: 10.1007/s00120-016-0161-y.
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Anabolic steroids abuse and male infertility.滥用合成代谢类固醇与男性不育。
Basic Clin Androl. 2016 Feb 6;26:2. doi: 10.1186/s12610-016-0029-4. eCollection 2016.
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Outcome of varicocele repair in men with nonobstructive azoospermia: systematic review and meta-analysis.非梗阻性无精子症男性精索静脉曲张修复术的结果:系统评价和荟萃分析。
Asian J Androl. 2016 Mar-Apr;18(2):246-53. doi: 10.4103/1008-682X.169562.
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Andrology. 2015 Nov;3(6):1050-3. doi: 10.1111/andr.12094. Epub 2015 Oct 7.
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N Engl J Med. 2015 May 28;372(22):2097-107. doi: 10.1056/NEJMoa1406192. Epub 2015 May 13.