Gerst P H, Fildes J, Baylor P, Zonszein J
Arch Surg. 1986 Jul;121(7):838-40. doi: 10.1001/archsurg.1986.01400070108022.
This report describes our experience with 12 patients with thyrotoxic Graves' disease who were prepared for thyroidectomy using only a long-acting orally administered beta-adrenergic blocking agent (nadolol or atenolol); iodides were not used. This form of preparation proved to be very effective, fast acting, and economical. It permitted rapid preparation of patients for surgery and resulted in excellent control of the manifestations of hyperthyroidism in the perioperative period. The surgery was relatively easy and bloodless, and there were no operative complications. We recommend that these long-acting beta-adrenergic blocking agents be considered as the preferred medication for the preparation of thyrotoxic patients for surgery.
本报告描述了我们对12例甲状腺毒性格雷夫斯病患者的治疗经验，这些患者仅使用长效口服β-肾上腺素能阻滞剂（纳多洛尔或阿替洛尔）进行甲状腺切除术准备；未使用碘剂。这种准备方式被证明非常有效、起效快且经济。它使患者能够迅速为手术做好准备，并在围手术期很好地控制了甲亢的症状。手术相对简单且无出血，也没有手术并发症。我们建议将这些长效β-肾上腺素能阻滞剂视为甲状腺毒症患者手术准备的首选药物。
