• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

先天性食管狭窄的临床研究:根据食管闭锁及气管食管瘘的关联进行比较

Clinical Study of Congenital Esophageal Stenosis: Comparison according to Association of Esophageal Atresia and Tracheoesophageal Fistula.

作者信息

Kim Soo-Hong, Kim Hyun-Young, Jung Sung-Eun, Lee Seong-Cheol, Park Kwi-Won

机构信息

Department of Pediatric Surgery, Pusan National University Children's Hospital, Yangsan, Korea.

Department of Pediatric Surgery, Seoul National University Children's Hospital, Seoul, Korea.

出版信息

Pediatr Gastroenterol Hepatol Nutr. 2017 Jun;20(2):79-86. doi: 10.5223/pghn.2017.20.2.79. Epub 2017 Jun 28.

DOI:10.5223/pghn.2017.20.2.79
PMID:28730131
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5517383/
Abstract

PURPOSE

Congenital esophageal atresia (CES) is a rare congenital disease. The severity of symptoms is variable; thus, diagnosis is difficult and tends to be delayed. CES is frequently accompanied by esophageal atresia (EA) with/without tracheoesophageal fistula (TEF). We investigated the characteristics of CES by reviewing our experience with CES patients and researched the differences between CES with EA-TEF and isolated CES.

METHODS

A total of 31 patients underwent operations for CES were reviewed retrospectively. The patients were divided into two groups according to the association with EA-TEF, and compared the differences.

RESULTS

Sixteen boys and 15 girls were included. The mean age at symptom onset was 8 months old, and the mean age at diagnosis was 21 months old. Nine patients with EA-TEF were included group A, whereas the other 22 patients were assigned to group B. There were no differences in sex, gestational age, associated anomalies and pathologic results between the groups. In group A, the age at diagnosis and age at surgery were younger than in group B despite the age at symptom occurrence being similar. Postoperative complications occurred only in group A.

CONCLUSION

In this study, symptoms occurred during the weaning period, and vomiting was the most frequent symptom. CES patients with EA-TEF tended to be diagnosed and treated earlier despite the age at symptom occurrence being similar. CES patients with EA-TEF had more postoperative complications; therefore, greater attention should be paid during the postoperative period.

摘要

目的

先天性食管闭锁(CES)是一种罕见的先天性疾病。症状的严重程度各不相同,因此诊断困难且往往延迟。CES常伴有食管闭锁(EA)合并或不合并气管食管瘘(TEF)。我们通过回顾CES患者的经验来研究CES的特征,并研究合并EA-TEF的CES与孤立性CES之间的差异。

方法

回顾性分析31例行CES手术的患者。根据是否合并EA-TEF将患者分为两组,并比较差异。

结果

纳入16例男孩和15例女孩。症状出现的平均年龄为8个月,诊断时的平均年龄为21个月。9例合并EA-TEF的患者纳入A组,其余22例患者分配到B组。两组在性别、孕周、合并畸形和病理结果方面无差异。在A组中,尽管症状出现的年龄相似,但诊断年龄和手术年龄比B组小。术后并发症仅发生在A组。

结论

在本研究中,症状出现在断奶期,呕吐是最常见的症状。合并EA-TEF的CES患者尽管症状出现的年龄相似,但往往诊断和治疗较早。合并EA-TEF的CES患者术后并发症更多;因此,术后应给予更多关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9f/5517383/c25f91f0dffd/pghn-20-79-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9f/5517383/82b938f71989/pghn-20-79-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9f/5517383/e234a88f6c8f/pghn-20-79-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9f/5517383/c25f91f0dffd/pghn-20-79-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9f/5517383/82b938f71989/pghn-20-79-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9f/5517383/e234a88f6c8f/pghn-20-79-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b9f/5517383/c25f91f0dffd/pghn-20-79-g003.jpg

相似文献

1
Clinical Study of Congenital Esophageal Stenosis: Comparison according to Association of Esophageal Atresia and Tracheoesophageal Fistula.先天性食管狭窄的临床研究:根据食管闭锁及气管食管瘘的关联进行比较
Pediatr Gastroenterol Hepatol Nutr. 2017 Jun;20(2):79-86. doi: 10.5223/pghn.2017.20.2.79. Epub 2017 Jun 28.
2
Congenital esophageal stenosis associated with esophageal atresia/tracheoesophageal fistula: clinical and radiologic features.先天性食管狭窄伴食管闭锁/气管食管瘘:临床和影像学特征。
Pediatr Radiol. 2010 Aug;40(8):1353-9. doi: 10.1007/s00247-010-1603-0. Epub 2010 Mar 10.
3
Clinical characteristics of congenital esophageal stenosis distal to associated esophageal atresia.先天性食管闭锁相关远端先天性食管狭窄的临床特征
Surgery. 2001 Jan;129(1):29-38. doi: 10.1067/msy.2001.109064.
4
Congenital esophageal stenosis associated with esophageal atresia.先天性食管狭窄合并食管闭锁。
Dis Esophagus. 2015 Apr;28(3):211-5. doi: 10.1111/dote.12176. Epub 2014 Jan 22.
5
Long-Term Outcomes of Patients with Tracheoesophageal Fistula/Esophageal Atresia: Survey Results from Tracheoesophageal Fistula/Esophageal Atresia Online Communities.气管食管瘘/食管闭锁患者的长期预后:气管食管瘘/食管闭锁在线社区的调查结果
Eur J Pediatr Surg. 2016 Dec;26(6):476-480. doi: 10.1055/s-0035-1570103. Epub 2015 Dec 21.
6
Esophageal atresia/tracheoesophageal fistula and associated congenital esophageal stenosis.食管闭锁/气管食管瘘及相关先天性食管狭窄
Pediatr Radiol. 1997 Jun;27(6):530-4. doi: 10.1007/s002470050174.
7
Balloon dilatation for congenital esophageal stenosis associated with esophageal atresia.球囊扩张术治疗先天性食管狭窄伴食管闭锁。
Pediatr Surg Int. 2024 Mar 22;40(1):89. doi: 10.1007/s00383-024-05652-w.
8
Characteristics and management of congenital esophageal stenosis: findings from a multicenter study.先天性食管狭窄的特征和处理:多中心研究的结果。
Orphanet J Rare Dis. 2013 Dec 1;8:186. doi: 10.1186/1750-1172-8-186.
9
Perioperative management and outcomes of esophageal atresia and tracheoesophageal fistula.食管闭锁及食管气管瘘的围手术期管理与预后
J Pediatr Surg. 2017 Aug;52(8):1245-1251. doi: 10.1016/j.jpedsurg.2016.11.046. Epub 2016 Dec 5.
10
Challenging surgical dogma in the management of proximal esophageal atresia with distal tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium.挑战近端食管闭锁合并远端气管食管瘘治疗中的外科教条:来自中西部儿科外科联盟的结果
J Pediatr Surg. 2018 Jul;53(7):1267-1272. doi: 10.1016/j.jpedsurg.2017.05.024. Epub 2017 Jun 1.

引用本文的文献

1
Neonatal Esophageal Stenosis: A Case Series.新生儿食管狭窄:病例系列
Sage Open Pediatr. 2025 Feb 25;12:30502225251309002. doi: 10.1177/30502225251309002. eCollection 2025 Jan-Dec.
2
Balloon dilatation for congenital esophageal stenosis associated with esophageal atresia.球囊扩张术治疗先天性食管狭窄伴食管闭锁。
Pediatr Surg Int. 2024 Mar 22;40(1):89. doi: 10.1007/s00383-024-05652-w.

本文引用的文献

1
Endoscopic management for congenital esophageal stenosis: A systematic review.先天性食管狭窄的内镜治疗:一项系统综述。
World J Gastrointest Endosc. 2015 Mar 16;7(3):183-91. doi: 10.4253/wjge.v7.i3.183.
2
Characteristics and management of congenital esophageal stenosis: findings from a multicenter study.先天性食管狭窄的特征和处理:多中心研究的结果。
Orphanet J Rare Dis. 2013 Dec 1;8:186. doi: 10.1186/1750-1172-8-186.
3
Endoscopic management of congenital esophageal stenosis.先天性食管狭窄的内镜治疗。
J Pediatr Surg. 2011 May;46(5):838-41. doi: 10.1016/j.jpedsurg.2011.02.010.
4
Congenital esophageal stenosis associated with esophageal atresia/tracheoesophageal fistula: clinical and radiologic features.先天性食管狭窄伴食管闭锁/气管食管瘘:临床和影像学特征。
Pediatr Radiol. 2010 Aug;40(8):1353-9. doi: 10.1007/s00247-010-1603-0. Epub 2010 Mar 10.
5
Oesophageal tracheobronchial remnants.食管气管支气管残余物。
Gastroenterol Clin Biol. 2008 Aug-Sep;32(8-9):779-81. doi: 10.1016/j.gcb.2008.04.023. Epub 2008 Jun 6.
6
Congenital esophageal stenosis owing to ectopic tracheobronchial remnants.由于异位气管支气管残余物导致的先天性食管狭窄。
J Pediatr Surg. 2004 Aug;39(8):1183-7. doi: 10.1016/j.jpedsurg.2004.04.039.
7
Esophageal motor function in congenital esophageal stenosis.先天性食管狭窄中的食管运动功能
J Pediatr Surg. 2003 Dec;38(12):1716-9. doi: 10.1016/j.jpedsurg.2003.08.020.
8
Clinical characteristics and management of congenital esophageal stenosis: a report on 14 cases.先天性食管狭窄的临床特征与治疗:14例报告
J Pediatr Surg. 2003 Apr;38(4):565-70. doi: 10.1053/jpsu.2003.50123.
9
Management of congenital esophageal stenosis.先天性食管狭窄的管理
J Pediatr Surg. 2002 Jul;37(7):1024-6. doi: 10.1053/jpsu.2002.33834.
10
Congenital esophageal stenosis: Therapeutic strategy based on etiology.先天性食管狭窄:基于病因的治疗策略。
J Pediatr Surg. 2002 Feb;37(2):197-201. doi: 10.1053/jpsu.2002.30254.