School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.
School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Sassoon Road, Hong Kong, China.
Curr Med Chem. 2018;25(40):5613-5630. doi: 10.2174/0929867324666170720165005.
The purpose of this account is to review the compounds capable of eliciting mitochondria-mediated apoptosis in cancer cells produced by medicinal fungi and plants. The medicinal fungi discussed encompass Cordyceps, Ganoderma species, Coriolus versicolor and Hypsizygus marmoreus. The medicinal plants discussed comprise Astragalus complanatus, Dendrobium spp, Dioscorea spp, Glycyrrhiza spp, Panax notoginseng, Panax ginseng, and Momordica charantia. These compounds have the potential of development into anticancer drugs.
本报告旨在综述药用真菌和植物中能够诱导癌细胞线粒体介导凋亡的化合物。所讨论的药用真菌包括冬虫夏草、灵芝属真菌、云芝和杏鲍菇。所讨论的药用植物包括甘草、石斛属植物、山药属植物、甘草属植物、三七、人参和苦瓜。这些化合物有可能开发成为抗癌药物。