Hadlandsmyth Katherine, Zimmerman M Bridget, Wajid Roohina, Sluka Kathleen A, Herr Keela, Clark Charles R, Noiseux Nicolas O, Callaghan John J, Rakel Barbara A
Department of Anesthesia, Carver College of Medicine.
Department of Biostatistics, College of Public Health.
Clin J Pain. 2018 Apr;34(4):332-338. doi: 10.1097/AJP.0000000000000540.
Although the majority of patients undergoing total knee arthroplasty (TKA) report substantial improvement in pain and function, a significant subset experience persistent postsurgical pain and dysfunction. Better understanding of the longitudinal postoperative course is needed, including the association between patient status following physical rehabilitation at 6-weeks post-TKA, to 6-months outcomes. This study aims to described the postoperative course of TKA and examine variables associated with change in pain and functioning between 6-weeks and 6-months post-TKA.
In this longitudinal study of 223 participants, assessments of analgesic intake, depression, anxiety, pain catastrophizing, dysfunction, resting and range of motion pain, and pain sensitivity were completed at 6-weeks post-TKA. Analgesic intake, pain ratings, and dysfunction data were also collected at 6-months post-TKA. Pain and dysfunction ratings were divided into none-mild and moderate-severe categories.
Between 6-weeks and 6-months post-TKA, 75% of the sample stayed in the same pain category, 20% improved, and 5% worsened. In terms of functional changes between 6 weeks and 6 months, 65% of the sample stayed in the same functional category, whereas 31% improved and 5% worsened.
These findings demonstrate that the majority of patients' pain and functioning remains stable between 6 weeks and 6 months post-TKA. However, a notable subset continues to improve or worsen in pain and functioning and the current study identifies variables associated with these changes.
尽管大多数接受全膝关节置换术(TKA)的患者报告疼痛和功能有显著改善,但仍有相当一部分患者术后存在持续疼痛和功能障碍。需要更好地了解术后的纵向病程,包括TKA术后6周身体康复后的患者状况与6个月结局之间的关联。本研究旨在描述TKA的术后病程,并检查与TKA术后6周和6个月之间疼痛和功能变化相关的变量。
在这项对223名参与者的纵向研究中,在TKA术后6周完成了对镇痛药物摄入量、抑郁、焦虑、疼痛灾难化、功能障碍、静息和活动范围疼痛以及疼痛敏感性的评估。在TKA术后6个月也收集了镇痛药物摄入量、疼痛评分和功能障碍数据。疼痛和功能障碍评分分为无-轻度和中度-重度两类。
在TKA术后6周和6个月之间,75%的样本疼痛类别保持不变,20%有所改善,5%恶化。在6周和6个月之间的功能变化方面,65%的样本功能类别保持不变,而31%有所改善,5%恶化。
这些发现表明,大多数患者在TKA术后6周和6个月之间疼痛和功能保持稳定。然而,有相当一部分患者的疼痛和功能继续改善或恶化,并且当前研究确定了与这些变化相关的变量。