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在乳腺癌放射治疗期间避免使用止汗剂:是无稽之谈还是合理建议?

Avoiding antiperspirants during breast radiation therapy: Myth or sound advice?

作者信息

Baumann Brian C, Zeng Chuan, Freedman Gary M, Verginadis Ioannis I, MacArthur Kelly M, Lin Lilie L, Vachani Carolyn, Koumenis Constantinos, Solberg Timothy D, Metz James M

机构信息

Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, United States; Department of Radiation Oncology, Washington University in Saint Louis, Saint Louis, MO, United States.

ProCure Proton Therapy Center, Somerset, NJ, United States.

出版信息

Radiother Oncol. 2017 Aug;124(2):204-207. doi: 10.1016/j.radonc.2017.06.021. Epub 2017 Jul 18.

DOI:10.1016/j.radonc.2017.06.021
PMID:28733055
Abstract

Breast cancer patients are typically advised to avoid antiperspirants for fear of increasing radiation dermatitis in the axilla. We hypothesized that antiperspirants would have minimal effect on skin dose. We found no difference in surface dose±antiperspirants using 6MV photons at gantry angles of 0°/30°/60°/90° regardless of aluminum concentration.

摘要

乳腺癌患者通常被建议避免使用止汗剂,因为担心会加重腋窝的放射性皮炎。我们推测止汗剂对皮肤剂量的影响极小。我们发现,无论铝浓度如何,在0°/30°/60°/90°的机架角度下使用6兆伏光子时,使用止汗剂与否的表面剂量并无差异。

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引用本文的文献

1
Assessing the Validity of Clinician Advice That Patients Avoid Use of Topical Agents Before Daily Radiotherapy Treatments.评估临床医生建议患者在每日放射治疗前避免使用局部制剂的有效性。
JAMA Oncol. 2018 Dec 1;4(12):1742-1748. doi: 10.1001/jamaoncol.2018.4292.