Tateyama Yukina, Oyama Kei, Shiraishi Masaru, Iijima Toshio, Tsutsui Ken-Ichiro
Division of Systems Neuroscience, Tohoku University Graduate School of Life Sciences, Sendai 980-8577, Japan.
Division of Systems Neuroscience, Tohoku University Graduate School of Life Sciences, Sendai 980-8577, Japan.
Neurosci Res. 2017 Dec;125:54-59. doi: 10.1016/j.neures.2017.07.003. Epub 2017 Jul 18.
Multi-unit recording has been one of the most widely used techniques to investigate the correlation between multiple neuronal activities and behavior. However, a common problem of currently used multi-channel electrodes is their physical weakness. In this study, we developed a novel multi-channel electrode with sufficient physical strength to penetrate a thickened dura mater. This electrode consists of low-cost materials and is easily fabricated, and it enables recording without removing dura mater, thereby reducing the risk of inflammation, infection, or brain herniation. The low-cost multi-channel electrode developed in this study would be a useful tool for chronic recording in behaving animals.
多单元记录一直是研究多个神经元活动与行为之间相关性最广泛使用的技术之一。然而，目前使用的多通道电极的一个常见问题是其物理强度较弱。在本研究中，我们开发了一种新型多通道电极，其具有足够的物理强度以穿透增厚的硬脑膜。该电极由低成本材料制成，易于制造，并且能够在不去除硬脑膜的情况下进行记录，从而降低炎症、感染或脑疝的风险。本研究中开发的低成本多通道电极将是用于行为动物慢性记录的有用工具。
