神经退行性疾病中的轴突运输功能障碍：开发疾病修饰疗法的“圣杯”？ - Suppr

Suppr

超能文献

Axonal transport dysfunction in neurodegenerative diseases: the "holy grail" for developing disease modifying therapies?

作者信息

Lamberts Jennifer T, Brundin Patrik

机构信息

College of Pharmacy, Ferris State University, Big Rapids, MI, USA.

Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI, USA.

出版信息

Neurobiol Dis. 2017 Sep;105:271-272. doi: 10.1016/j.nbd.2017.06.018.

DOI:10.1016/j.nbd.2017.06.018

PMID:28734388

Abstract

摘要

相似文献

Axonal transport dysfunction in neurodegenerative diseases: the "holy grail" for developing disease modifying therapies?

Neurobiol Dis. 2017 Sep;105:271-272. doi: 10.1016/j.nbd.2017.06.018.

Releasing the brake: restoring fast axonal transport in neurodegenerative disorders.

Trends Cell Biol. 2013 Dec;23(12):634-43. doi: 10.1016/j.tcb.2013.08.007. Epub 2013 Sep 30.

Axonal transport and neurodegenerative disease.

Biochim Biophys Acta. 2006 Nov-Dec;1762(11-12):1094-108. doi: 10.1016/j.bbadis.2006.04.002. Epub 2006 Apr 19.

Molecular landmarks along the axonal route: axonal transport in health and disease.

Curr Opin Cell Biol. 2008 Aug;20(4):445-53. doi: 10.1016/j.ceb.2008.04.002. Epub 2008 May 19.

Potential therapeutic targets in polyglutamine-mediated diseases.

Expert Rev Neurother. 2014 Oct;14(10):1215-28. doi: 10.1586/14737175.2014.956727. Epub 2014 Sep 4.

Axonal transport defects: a common theme in neurodegenerative diseases.

Acta Neuropathol. 2005 Jan;109(1):5-13. doi: 10.1007/s00401-004-0952-x. Epub 2005 Jan 12.

α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7813-7818. doi: 10.1073/pnas.1713129115. Epub 2018 Jul 10.

Regulation of Axonal Transport by Protein Kinases.

Trends Biochem Sci. 2015 Oct;40(10):597-610. doi: 10.1016/j.tibs.2015.08.003.

Axonal transport failure in neurodegenerative disorders: the case of Huntington's disease.

Pathol Biol (Paris). 2005 May;53(4):189-92. doi: 10.1016/j.patbio.2004.12.008.

To the end of the line: Axonal mRNA transport and local translation in health and neurodegenerative disease.

Dev Neurobiol. 2018 Mar;78(3):209-220. doi: 10.1002/dneu.22555. Epub 2017 Nov 13.

引用本文的文献

Mitochondrial Dysfunction and Oxidative Stress in Alzheimer's Disease.

Front Aging Neurosci. 2021 Feb 18;13:617588. doi: 10.3389/fnagi.2021.617588. eCollection 2021.

The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration.

Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4971-4982. doi: 10.1073/pnas.1913904117. Epub 2020 Feb 19.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

相似文献

Axonal transport dysfunction in neurodegenerative diseases: the "holy grail" for developing disease modifying therapies?

Neurobiol Dis. 2017 Sep;105:271-272. doi: 10.1016/j.nbd.2017.06.018.

Releasing the brake: restoring fast axonal transport in neurodegenerative disorders.

Trends Cell Biol. 2013 Dec;23(12):634-43. doi: 10.1016/j.tcb.2013.08.007. Epub 2013 Sep 30.

Axonal transport and neurodegenerative disease.

Biochim Biophys Acta. 2006 Nov-Dec;1762(11-12):1094-108. doi: 10.1016/j.bbadis.2006.04.002. Epub 2006 Apr 19.

Molecular landmarks along the axonal route: axonal transport in health and disease.

Curr Opin Cell Biol. 2008 Aug;20(4):445-53. doi: 10.1016/j.ceb.2008.04.002. Epub 2008 May 19.

Potential therapeutic targets in polyglutamine-mediated diseases.

Expert Rev Neurother. 2014 Oct;14(10):1215-28. doi: 10.1586/14737175.2014.956727. Epub 2014 Sep 4.

Axonal transport defects: a common theme in neurodegenerative diseases.

Acta Neuropathol. 2005 Jan;109(1):5-13. doi: 10.1007/s00401-004-0952-x. Epub 2005 Jan 12.

α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7813-7818. doi: 10.1073/pnas.1713129115. Epub 2018 Jul 10.

Regulation of Axonal Transport by Protein Kinases.

Trends Biochem Sci. 2015 Oct;40(10):597-610. doi: 10.1016/j.tibs.2015.08.003.

Axonal transport failure in neurodegenerative disorders: the case of Huntington's disease.

Pathol Biol (Paris). 2005 May;53(4):189-92. doi: 10.1016/j.patbio.2004.12.008.

To the end of the line: Axonal mRNA transport and local translation in health and neurodegenerative disease.

Dev Neurobiol. 2018 Mar;78(3):209-220. doi: 10.1002/dneu.22555. Epub 2017 Nov 13.

引用本文的文献

Mitochondrial Dysfunction and Oxidative Stress in Alzheimer's Disease.

Front Aging Neurosci. 2021 Feb 18;13:617588. doi: 10.3389/fnagi.2021.617588. eCollection 2021.

The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration.

Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4971-4982. doi: 10.1073/pnas.1913904117. Epub 2020 Feb 19.