Tanaka Shin, Miyoshi Kentaroh, Sugimoto Seiichiro, Yamane Masaomi, Kobayashi Motomu, Oto Takahiro
Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan.
Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan.
Ann Thorac Surg. 2017 Aug;104(2):e177-e179. doi: 10.1016/j.athoracsur.2017.03.019.
A successful outcome after lung transplant was achieved using lungs donated from a teenage boy who underwent prolonged mechanical ventilation. The donor experienced hypoxic brain damage and was declared brain dead 324 days after tracheal intubation. At the time of referral, the donor's lungs revealed diffuse radiologic infiltration and atelectasis but excellent function, with a PaO/FiO ratio of 450. The lungs were transplanted to a 10-year-old girl with bronchiolitis obliterans. She developed grade 2 primary graft dysfunction, but recovered quickly. She is doing well and has not experienced any other critical adverse events 12 months after lung transplantation.
使用一名接受长时间机械通气的青少年男孩捐赠的肺成功完成了肺移植。供体经历了缺氧性脑损伤，在气管插管324天后被宣布脑死亡。转诊时，供体的肺部显示出弥漫性放射学浸润和肺不张，但功能良好，动脉血氧分压与吸入氧浓度比值为450。这些肺被移植给一名患有闭塞性细支气管炎的10岁女孩。她出现了2级原发性移植物功能障碍，但恢复迅速。肺移植12个月后，她情况良好，未发生任何其他严重不良事件。
