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经导管动脉栓塞异常血管治疗保守治疗无效的外侧上髁炎:一项为期2年随访的初步研究

Transcatheter arterial embolization of abnormal vessels as a treatment for lateral epicondylitis refractory to conservative treatment: a pilot study with a 2-year follow-up.

作者信息

Iwamoto Wataru, Okuno Yuji, Matsumura Noboru, Kaneko Takao, Ikegami Hiroyasu

机构信息

Institute for Integrated Sports Medicine, Keio University School of Medicine, Tokyo, Japan.

Musculoskeletal Intervention Center, Edogawa Hospital, Tokyo, Japan.

出版信息

J Shoulder Elbow Surg. 2017 Aug;26(8):1335-1341. doi: 10.1016/j.jse.2017.03.026.

DOI:10.1016/j.jse.2017.03.026
PMID:28734535
Abstract

BACKGROUND

Abnormal vessels and accompanying nerves are possible sources of pain with lateral epicondylitis. The purpose of this study was to describe the safety and efficacy of transcatheter arterial embolization (TAE) for lateral epicondylitis resistant to conservative treatment.

METHODS

This prospective study was conducted in 24 patients with lateral epicondylitis resistant to conservative treatments for more than 3 months, with a symptom duration longer than 6 months, and with moderate to severe pain who were treated with TAE between March 2013 and October 2014. Two patients were lost to follow-up, and the remaining 22 patients were followed up for 2 years after TAE.

RESULTS

Abnormal vessels were identified in all of the patients. No major adverse events were observed. The Quick Disabilities of the Arm, Shoulder and Hand scores at baseline significantly decreased at 1, 3, 6, and 24 months after treatment (50.8 vs 23.4, 8.3, 5.3, and 2.7, respectively; all P < .001). There was a statistically significant (P < .001) change from baseline to the last observed value in all of the clinical parameters, including visual analog scale pain score, Patient-Rated Tennis Elbow Evaluation score, and pain-free grip strength. Magnetic resonance images obtained 2 years after TAE showed an improvement in tendinosis and tear scores compared with baseline, and no patients showed bone marrow necrosis, obvious cartilage loss, or muscle atrophy.

CONCLUSION

TAE could be one possible treatment option for patients with lateral epicondylitis that fails to improve with conservative treatments.

摘要

背景

异常血管及伴行神经可能是外侧上髁炎疼痛的来源。本研究旨在描述经导管动脉栓塞术(TAE)治疗对保守治疗无效的外侧上髁炎的安全性和有效性。

方法

本前瞻性研究纳入了24例对保守治疗无效超过3个月、症状持续时间超过6个月且疼痛为中度至重度的外侧上髁炎患者,于2013年3月至2014年10月接受TAE治疗。2例患者失访,其余22例患者在TAE术后随访2年。

结果

所有患者均发现异常血管。未观察到重大不良事件。治疗后1、3、6和24个月时,手臂、肩部和手部快速残疾评分较基线时显著降低(分别为50.8对23.4、8.3、5.3和2.7;均P <.001)。所有临床参数(包括视觉模拟评分疼痛评分、患者网球肘评估评分和无痛握力)从基线到最后观察值均有统计学显著变化(P <.001)。TAE术后2年获得的磁共振成像显示,与基线相比,肌腱病和撕裂评分有所改善,且无患者出现骨髓坏死、明显软骨丢失或肌肉萎缩。

结论

对于保守治疗无效的外侧上髁炎患者,TAE可能是一种可行的治疗选择。

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