Fischer M V, Eibach J, Schmidt M
Anasth Intensivther Notfallmed. 1986 Apr;21(2):78-81.
The incidence of pain associated with advanced cancer is very high. In addition, most patients are also suffering from emotional and social problems. In the choice of pain treatment the different processes of nociception have to be considered. Thus non-narcotic analgesics and psychotropic agents may be combined to reduce opiate requirements. Oral medication is to be preferred and should be given on a strict schedule. Pain syndromes irresponsive to this pharmacological treatment are indications for neurosurgical procedures, epidural opiates and neurolytic nerve blocks.
晚期癌症相关疼痛的发生率非常高。此外,大多数患者还存在情绪和社会问题。在选择疼痛治疗方法时,必须考虑伤害感受的不同过程。因此,非麻醉性镇痛药和精神药物可联合使用以减少阿片类药物的用量。应优先选择口服药物,并应严格按照时间表给药。对这种药物治疗无反应的疼痛综合征是神经外科手术、硬膜外使用阿片类药物和神经溶解神经阻滞的指征。