Lentine Krista L, Kasiske Bertram L, Levey Andrew S, Adams Patricia L, Alberú Josefina, Bakr Mohamed A, Gallon Lorenzo, Garvey Catherine A, Guleria Sandeep, Li Philip Kam-Tao, Segev Dorry L, Taler Sandra J, Tanabe Kazunari, Wright Linda, Zeier Martin G, Cheung Michael, Garg Amit X
1 Saint Louis University School of Medicine, St. Louis, MO. 2 Hennepin County Medical Center, Minneapolis, MN. 3 Tufts Medical Center, Boston, MA. 4 Wake Forest School of Medicine, Winston-Salem, NC. 5 Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico. 6 Mansoura University, Mansoura, Egypt. 7 Northwestern University, Chicago, IL. 8 University of Minnesota, Minneapolis, MN. 9 Indraprastha Apollo Hospitals, New Delhi, India. 10 Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China. 11 Johns Hopkins University School of Medicine, Baltimore, MD. 12 Mayo Clinic, Rochester, MN. 13 Tokyo Women's Medical University, Tokyo, Japan. 14 University of Toronto, Toronto, Canada. 15 University Hospital Heidelberg, Heidelberg, Germany. 16 KDIGO, Brussels, Belgium. 17 Western University, London, Ontario, Canada.
Transplantation. 2017 Aug;101(8):1783-1792. doi: 10.1097/TP.0000000000001770.
Kidney Disease: Improving Global Outcomes (KDIGO) engaged an evidence review team and convened a work group to produce a guideline to evaluate and manage candidates for living kidney donation. The evidence for most guideline recommendations is sparse and many "ungraded" expert consensus recommendations were made to guide the donor candidate evaluation and care before, during, and after donation. The guideline advocates for replacing decisions based on assessments of single risk factors in isolation with a comprehensive approach to risk assessment using the best available evidence. The approach to simultaneous consideration of each candidate's profile of demographic and health characteristics advances a new framework for assessing donor candidate risk and for defensible shared decision making.
改善全球肾脏病预后组织(KDIGO)组建了一个证据审查团队,并召集了一个工作组来制定一份评估和管理活体肾捐赠候选者的指南。大多数指南建议的证据都很稀少,因此制定了许多“未分级”的专家共识建议,以指导捐赠候选者在捐赠前、捐赠期间和捐赠后的评估及护理。该指南主张摒弃孤立地基于单一风险因素评估的决策方式,采用基于现有最佳证据的全面风险评估方法。同时考虑每位候选者的人口统计学和健康特征概况的方法,为评估捐赠候选者风险及进行合理的共同决策提出了一个新框架。