de Andrade Paulo Evaristo, do Amaral Joice Anaize Tonon, Paiva Laércio da Silva, Adami Fernando, Raimudo Juliana Zangirolami, Valenti Vitor Engrácia, Abreu Luiz Carlos de, Raimundo Rodrigo Daminello
a Laboratório de Delineamento de Estudos e Escrita Científica , Faculdade de Medicina do ABC , Santo André , SP , Brasil.
b Faculdade de Medicina , Universidade de São Paulo-USP , São Paulo , SP , Brasil.
Blood Press. 2017 Dec;26(6):350-358. doi: 10.1080/08037051.2017.1354285. Epub 2017 Jul 24.
The elderly population grows globally every day, and along with it the incidence of high blood pressure also grows, following these data scientists seek tools to improve the health of this population, a widely used tool for assessing cardiovascular function is the heart rate variability(HRV), that is a mecanism that allows the investigation of oscillations in the intervals between consecutive heart beats (RR intervals). There are already studies on the autonomic nervous system in the elderly population, however, these studies investigated normotensive patients and there is little research in hypertensive patients.
To compare the cardiac autonomic modulation between healthy elderly and hypertensive elderly.
The total sample was 80 elderly people- 40 healthy elderly and 40 elderly (HBP). Anthropometric data, HRV analysis and IPAQ questionnaire were collected. For the analysis of cardiac modulation data in the time domain (pNN50, SDNN and RMSSD) and frequency domain (LF and HF). The geometric analysis (RRtri, TINN, SD1, SD2 and SD1/SD2 ratios).
In the time domain the MeanRR index presented a HAS increase 832.35 ± 104.46 ms vs control 782.73 ± 112.78 ms (p = 0.040). In the SDNN, there was a 58.35ms decrease vs the SAH 43.15 ms (p = 0.030). In the frequency domain, HF decreased control 247.00 ms2 vs HAS 157.00 ms2 (p = 0.002). In the geometric, the TINN and SD2 in the HAS group decreased in relation to the control from 203.38 ± 80.26 ms to 161.83 ± 53.25 ms (p = 0.018) and from 71.95 ms to 59.40 ms (p = 0.051). The mean SD1/SD2 ratio showed an increase between the Control and SAH groups from 0.22 ± 0.10 to 4.09 ± 1.18 and there was a statistical difference (p = 0.001).
Hypertensive elderly patients present decreased heart rate variability and decreased parasympathetic modulation when compared to normotensive elderly.
全球老年人口每天都在增长,高血压的发病率也随之上升。基于这些数据,科学家们寻求改善这一人群健康状况的工具。一种广泛用于评估心血管功能的工具是心率变异性(HRV),它是一种用于研究连续心跳间期(RR间期)振荡的机制。已有针对老年人群自主神经系统的研究,然而,这些研究调查的是血压正常的患者,而高血压患者的相关研究较少。
比较健康老年人与高血压老年人的心脏自主神经调节情况。
总样本为80名老年人,其中40名健康老年人和40名高血压老年人。收集了人体测量数据、HRV分析和国际体力活动问卷(IPAQ)。用于分析时域(pNN50、SDNN和RMSSD)和频域(LF和HF)的心脏调节数据,以及几何分析(RRtri、TINN、SD1、SD2和SD1/SD2比值)。
在时域中,平均RR指数显示高血压组增加至832.35±104.46毫秒,而对照组为782.73±112.78毫秒(p = 0.040)。在SDNN方面,与高血压组相比下降了58.35毫秒,而高血压组下降了43.15毫秒(p = 0.030)。在频域中,高频(HF)对照组为247.00毫秒²,高血压组为157.00毫秒²(p = 0.002)。在几何分析中,高血压组的TINN和SD2相对于对照组有所下降,从203.38±80.26毫秒降至161.83±53.25毫秒(p = 0.018),从71.95毫秒降至59.40毫秒(p = 0.051)。对照组和高血压组的平均SD1/SD2比值从0.22±0.10增加到4.09±1.18,且存在统计学差异(p = 0.001)。
与血压正常的老年人相比,高血压老年患者的心率变异性降低,副交感神经调节功能下降。