剖宫产术后股直肌鞘布比卡因与鞘内布比卡因、布比卡因与鞘内吗啡与布比卡因和吗啡比较的随机对照试验。
A randomised, controlled trial of rectus sheath bupivacaine and intrathecal bupivacaine, without or with intrathecal morphine, vs. intrathecal bupivacaine and morphine after caesarean section.
机构信息
Department of Obstetrics and Gynaecology, Queen Mary Hospital, The University of Hong Kong, Hong Kong.
Department of Anaesthesiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong.
出版信息
Anaesthesia. 2017 Oct;72(10):1225-1229. doi: 10.1111/anae.13998. Epub 2017 Jul 25.
We recruited 144 women of whom 131 underwent scheduled caesarean section and were allocated to intrathecal bupivacaine without (46) or with (47) morphine and postoperative rectus sheath bupivacaine; or intrathecal bupivacaine with morphine and postoperative rectus sheath saline (38). We measured postoperative pain with a 10-point numeric rating scale. The mean (SD) areas under the curve for pain on movement during 48 postoperative hours were 273.5 (63.6), 223.8 (80.7) and 223.8 (80.7), respectively, p = 0.008. There was no difference between women who had intrathecal morphine with or without rectus sheath bupivacaine, p = 1. The equivalent values for pain at rest were 160.8 (64.7), 85.8 (79.4) and 82.8 (74.3), respectively, p < 0.001. There was no difference between women who had intrathecal morphine with or without rectus sheath bupivacaine, p = 0.98.
我们招募了 144 名女性，其中 131 名接受了计划剖宫产，并被分配到鞘内布比卡因（46 例）或鞘内布比卡因加吗啡和术后腹直肌鞘布比卡因（47 例）；或鞘内布比卡因加吗啡和术后腹直肌鞘生理盐水（38 例）。我们使用 10 分数字评分量表来测量术后疼痛。术后 48 小时内运动时疼痛的曲线下面积分别为 273.5（63.6）、223.8（80.7）和 223.8（80.7），p = 0.008。鞘内吗啡加或不加腹直肌鞘布比卡因的女性之间没有差异，p = 1。静息时疼痛的等效值分别为 160.8（64.7）、85.8（79.4）和 82.8（74.3），p < 0.001。鞘内吗啡加或不加腹直肌鞘布比卡因的女性之间没有差异，p = 0.98。
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