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子宫内膜异位症与生育力保护

Endometriosis and Fertility Preservation.

作者信息

Barnett Rebecca, Banks Nicole, Decherney Alan H

机构信息

*Robert Wood Johnson Medical School, New Brunswick, New Jersey †NICHD/NIH, Bethesda, Maryland.

出版信息

Clin Obstet Gynecol. 2017 Sep;60(3):517-523. doi: 10.1097/GRF.0000000000000311.

Abstract

Endometriosis is common, affecting 5% to 10% of reproductive age women. Nearly half of women with surgical evidence of endometriosis fail to achieve spontaneous pregnancy. Surgical treatment of endometriosis can be detrimental to ovarian reserve. In the absence of surgical intervention, ovarian reserve may still be negatively impacted over time. Fertility preservation was developed for women requiring gonadotoxic treatments. Improved methods have led to greater consideration of offering these services to women with other disease processes that threaten ovarian reserve. This chapter will present the debate regarding use of fertility preservation in management of endometriosis, and outline the need for further studies.

摘要

子宫内膜异位症很常见,影响着5%至10%的育龄妇女。近一半有子宫内膜异位症手术证据的女性无法自然受孕。子宫内膜异位症的手术治疗可能会损害卵巢储备功能。在没有手术干预的情况下,随着时间的推移,卵巢储备功能仍可能受到负面影响。生育力保存是为需要进行性腺毒性治疗的女性而开发的。改进的方法使得人们更多地考虑为患有其他威胁卵巢储备功能的疾病的女性提供这些服务。本章将阐述关于在子宫内膜异位症管理中使用生育力保存的争议,并概述进一步研究的必要性。

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