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腰椎骨盆角、T1 骨盆角的腰椎成分与 HRQOL、PI-LL 不匹配相关,可预测整体对线。

The Lumbar Pelvic Angle, the Lumbar Component of the T1 Pelvic Angle, Correlates With HRQOL, PI-LL Mismatch, and it Predicts Global Alignment.

机构信息

Department of Orthopaedic Surgery, New York University Hospital for Joint Diseases, New York, NY.

Deparment of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY.

出版信息

Spine (Phila Pa 1976). 2018 May 15;43(10):681-687. doi: 10.1097/BRS.0000000000002346.

Abstract

STUDY DESIGN

Prospective multicenter analysis of adult spinal deformity (ASD) patients.

OBJECTIVE

The aim of this study was to introduce the lumbar pelvic angle (LPA), a novel parameter of spinopelvic alignment.

SUMMARY OF BACKGROUND DATA

The T1 pelvic angle (TPA), a measure of global spinopelvic alignment, correlates with health-related quality of life (HRQOL), but it may not be measureable on all intraoperative x-rays. In patients with previous interbody fusion at L5-S1, the plane of the S1 endplate can be blurred, creating error in pelvic incidence and lumbar lordosis (PI-LL) measure. The LPA is more readily measured on intraoperative imaging than the TPA.

METHODS

ASD patients were included with either coronal Cobb angle >20°, sagittal vertical axis (SVA) >5 cm, thoracic kyphosis >60°, or pelvic tilt (PT) >25°. Measures of disability included Oswestry Disability Index (ODI), Scoliosis Research Society (SRS), and Short Form (SF)-36. Baseline and 2-year follow-up radiographic and HRQOL outcomes were evaluated. Linear regressions compared LPA with radiographic parameters and HRQOL.

RESULTS

A total of 852 ASD patients (407 operative) were enrolled (mean age 53.7). Baseline LPA correlated with PI-LL (r = 0.79), PT (r = 0.78), TPA (r = 0.82), and SVA (r = 0.61) (all P < 0.001). PI-LL, LPA, and TPA correlated with ODI (r = 0.42/0.29/0.45), SF-36 physical component score (-0.43/-0.28/-0.45) SRS (-0.354/-0.23/-0.37) with all P < 0.001. At 2 years' follow-up, LPA correlated with PI-LL (r = 0.77), PT (r = 0.78), TPA (r = 0.83), and SVA (r = 0.57) (all P < 0.001). Categorizing patients by increasing LPA (<7°; 7°-15°; >15°) revealed progressive increases in all HRQOL, PI-LL (-3.2°/12.7°/32.4°), and TPA (9.7°/20.1°/34.6°) with all P < 0.001. Moderate disability (ODI = 40) corresponded to LPA 10.1°, PI-LL 12.6°, and TPA 20.6°. Mild disability (ODI = 20) corresponded to LPA 7.2°, PI-LL 4.2°, and TPA 14.7°.

CONCLUSION

LPA correlates with TPA, PI-LL, and HRQOL in ASD patients. LPA can be used as an intraoperative tool to gauge correction with a target LPA of <7.2°. LPA predicts global alignment, as it correlates with baseline and 2-year TPA and SVA. Along with the cervical-thoracic pelvic angle and TPA, LPA completes the fan of spinopelvic alignment.

LEVEL OF EVIDENCE

摘要

研究设计

成人脊柱畸形(ASD)患者的前瞻性多中心分析。

目的

本研究旨在介绍腰椎骨盆角(LPA),这是一种新的脊柱骨盆对线参数。

背景资料总结

T1 骨盆角(TPA)是一种整体脊柱骨盆对线的测量指标,与健康相关的生活质量(HRQOL)相关,但它可能无法在所有术中 X 光片上测量。在既往 L5-S1 椎间融合的患者中,S1 终板平面可能会变得模糊,导致骨盆入射角和腰椎前凸(PI-LL)测量出现误差。LPA 比 TPA 更容易在术中成像上测量。

方法

纳入冠状 Cobb 角>20°、矢状垂直轴(SVA)>5cm、胸腰椎后凸>60°或骨盆倾斜(PT)>25°的 ASD 患者。包括残疾的测量指标包括 Oswestry 残疾指数(ODI)、脊柱侧凸研究协会(SRS)和简短形式(SF)-36。评估基线和 2 年随访的影像学和 HRQOL 结果。线性回归比较 LPA 与影像学参数和 HRQOL。

结果

共纳入 852 例 ASD 患者(407 例手术)(平均年龄 53.7 岁)。基线 LPA 与 PI-LL(r=0.79)、PT(r=0.78)、TPA(r=0.82)和 SVA(r=0.61)(均 P<0.001)相关。PI-LL、LPA 和 TPA 与 ODI(r=0.42/0.29/0.45)、SF-36 生理成分评分(-0.43/-0.28/-0.45)、SRS(-0.354/-0.23/-0.37)相关(均 P<0.001)。在 2 年的随访中,LPA 与 PI-LL(r=0.77)、PT(r=0.78)、TPA(r=0.83)和 SVA(r=0.57)(均 P<0.001)相关。将患者按 LPA 增加(<7°;7°-15°;>15°)分类,所有 HRQOL、PI-LL(-3.2°/12.7°/32.4°)和 TPA(9.7°/20.1°/34.6°)均逐渐增加(均 P<0.001)。中度残疾(ODI=40)对应 LPA 为 10.1°、PI-LL 为 12.6°和 TPA 为 20.6°。轻度残疾(ODI=20)对应 LPA 为 7.2°、PI-LL 为 4.2°和 TPA 为 14.7°。

结论

LPA 与 ASD 患者的 TPA、PI-LL 和 HRQOL 相关。LPA 可以作为术中工具来评估以<7.2°为目标的矫正情况。LPA 预测整体对线,因为它与基线和 2 年 TPA 和 SVA 相关。与颈椎-胸腰椎骨盆角和 TPA 一起,LPA 完成了脊柱骨盆对线的扇形。

证据水平

3 级。

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