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越多越好?整合椎体骨盆角(VPA)PJK 阈值到现有的脊柱畸形矫正术后预防机械并发症的的评估方案中。

The more the better? Integration of vertebral pelvic angles (VPA) PJK thresholds to existing alignment schemas for prevention of mechanical complications after adult spinal deformity surgery.

机构信息

Department of Neurological and Orthopedic Surgery, Duke Spine Center, Duke University School of Medicine, 40 Duke Medicine Circle, 27710-4000, Durham, NC, USA.

Department of Orthopedics, Hospital for Special Surgery, New York, NY, USA.

出版信息

Eur Spine J. 2024 Oct;33(10):3887-3893. doi: 10.1007/s00586-024-08458-5. Epub 2024 Sep 2.

Abstract

PURPOSE

While existing adult spinal deformity (ASD) alignment schemas acknowledge the dynamic relationship between the pelvis and spine, consideration of vertebral pelvic angles (VPA) thresholds for PJK may provide further insight into the relationship of each individual vertebra to the pelvis, which may allow for greater individualization of operative targets. Herein, we examine VPA's utility in preventing mechanical complications and its possible unification with prevalent scoring systems.

METHODS

In a retrospective cohort study of a prospectively collected database, operative ASD patients ≥ 18 years with complete baseline (BL) and two-year (Y) operative, radiographic, and health-related quality of life data were included. Descriptive analyses, means comparison, and logistic regression tests were applied to explore demographic and surgical differences, as well as the impact of alignment goals on outcomes. Cohorts were grouped as patients who met VPA non-PJK thresholds, as defined by Duvvuri et al. 2023 alone versus traditional GAP/SAAS alignment matching versus combined VPA + SAAS + GAP. The Non-PJK VPA validated mean for L1PA was 10.4 ± 7.0 and T9PA 8.9 ± 7.5.

RESULTS

398 patients met inclusion criteria (mean age 61 ± 14 years, 78% female, BL BMI 27 ± 6, BL CCI 2 ± 2). At baseline, mean vertebral pelvic angles were as follows: T1PA: 24 ± 14; T4PA 20 ± 13, T9PA 15 ± 12, L1PA 11 ± 10, L4PA 11 ± 6. Mean vertebral pelvic angles at 6 W postoperatively: T1PA 16 ± 10, T4PA 12 ± 10, T9PA 8 ± 9, L1PA 9 ± 8, L4PA 11 ± 5. 240 (60%) patients attained optimal L1PA, while 104 patients (26.1%) reached non-PJK mean for T9PA. 89 patients (22%) were optimal by both VPA standards. VPA-Optimal group demonstrated significantly lower rates of 1Y PJK (17% v 83%, p = 0.042) and PJF by 2Y (7% v. 93%, p = 0.038). When patients attained VPA goals in addition to GAP/SAAS goals at 6 W, they demonstrated significantly lower rates of Y1 PJK (p = 0.026) and Y1 and Y2 PJF. Those with optimal VPA registered greater SRS-22 scores across multiple domains (p < 0.02) as well as a greater rate of normal neurological examination at 6 W (p = 0.048).

CONCLUSIONS

Vertebral pelvic angles are a reliable measure of global alignment, and respecting certain targets may help prevent development of PJK/PJF. The value of VPA can be augmented through integration with GAP/SAAS frameworks to prevent complications and improve quality of life.

摘要

目的

虽然现有的成人脊柱畸形(ASD)对线方案承认了骨盆和脊柱之间的动态关系,但考虑到骨盆矢状角(VPA)对于 PJK 的阈值可能会进一步了解每个椎体与骨盆的关系,这可能允许对手术目标进行更大的个体化。在此,我们研究了 VPA 在预防机械并发症方面的作用及其与现有评分系统的可能统一。

方法

在一项前瞻性收集数据库的回顾性队列研究中,纳入了年龄≥ 18 岁的手术 ASD 患者,这些患者具有完整的基线(BL)和两年(Y)手术、影像学和健康相关生活质量数据。应用描述性分析、均值比较和逻辑回归检验,探讨了人口统计学和手术差异,以及对线目标对结果的影响。队列分为满足 Duvvuri 等人定义的 VPA 非 PJK 阈值的患者组,2023 年单独使用 VPA 而非 Duvvuri 等人定义的 PJK 阈值,与传统的 GAP/SAAS 对线匹配,或与 VPA 联合使用。L1PA 的验证性非 PJK VPA 平均值为 10.4±7.0,T9PA 为 8.9±7.5。

结果

398 名患者符合纳入标准(平均年龄 61±14 岁,78%为女性,BL BMI 27±6,BL CCI 2±2)。基线时,平均椎体骨盆角度如下:T1PA:24±14;T4PA 20±13,T9PA 15±12,L1PA 11±10,L4PA 11±6。术后 6 周的平均椎体骨盆角度为:T1PA 16±10,T4PA 12±10,T9PA 8±9,L1PA 9±8,L4PA 11±5。240(60%)名患者达到了理想的 L1PA,而 104 名患者(26.1%)达到了 T9PA 的非 PJK 平均值。89 名患者(22%)同时达到了 VPA 标准。VPA 优化组 1Y PJK 发生率明显较低(17%比 83%,p=0.042),2Y PJP 发生率明显较低(7%比 93%,p=0.038)。当患者在术后 6 周达到 GAP/SAAS 目标和 VPA 目标时,Y1 PJK(p=0.026)和 Y1 和 Y2 PJP 发生率明显较低。VPA 优化组的 SRS-22 评分在多个领域均有显著提高(p<0.02),且在术后 6 周时,神经功能检查正常的比例更高(p=0.048)。

结论

椎体骨盆角度是一种可靠的整体对线测量方法,尊重某些目标可能有助于预防 PJK/PJP 的发生。通过与 GAP/SAAS 框架的整合,可以增强 VPA 的价值,以预防并发症并提高生活质量。

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