Departments of Urology, China Rehabilitation Research Centre and Capital Medical University, Beijing Key Laboratory of Neural Injury and Rehabilitation and Center of Neural Injury and Repair, Beijing Institute for Brain Disorders, Beijing, China.
Departments of Urology, China Rehabilitation Research Centre and Capital Medical University, Beijing Key Laboratory of Neural Injury and Rehabilitation and Center of Neural Injury and Repair, Beijing Institute for Brain Disorders, Beijing, China.
J Urol. 2018 Jan;199(1):200-205. doi: 10.1016/j.juro.2017.07.073. Epub 2017 Jul 23.
We reviewed our experience with the effectiveness and complications of augmentation cystoplasty with or without nonrefluxing ureteral reimplantation in adult patients with long-standing bladder dysfunction.
We retrospectively reviewed the records of 173 patients who underwent augmentation cystoplasty with or without ureteral reimplantation at our center from July 2005 to July 2016. Clinical data, and magnetic resonance urography and videourodynamic parameters were collected. Upper urinary tract dilatation and vesicoureteral reflux grading systems were used to evaluate upper urinary tract function. Postoperative complications were evaluated.
Ureteral reimplantation was performed in 160 patients (266 ureteral units) and 120 ureteral units were simultaneously managed by tailoring and/or ureterolysis. Mean followup was 44.4 months (range 3 to 108). Mean maximum bladder capacity and bladder compliance significantly increased (p <0.0001), and maximum detrusor pressure and serum creatinine decreased compared with preoperative levels (p <0.05). Upper urinary tract dilatation and vesicoureteral reflux significantly improved after surgery. Postoperative complications included persistent vesicoureteral reflux in 1 patient (0.6%), anastomotic stricture in 14 ureteral units (5.3%), bowel dysfunction in 11 patients (6.4%), a need for laparotomy in 4 (2.3%), urinary tract stone in 15 (8.7%) and deteriorating renal function in 9 (5.2%).
This retrospective study indicates that ureteral reimplantation concomitant with augmentation cystoplasty may be beneficial in patients with low pressure or high grade vesicoureteral reflux, ureterovesical junction obstruction or ureteral tortuosity, and adhesions and/or severe upper urinary tract dilatation, especially in those with a long medical history.
我们回顾了在长期膀胱功能障碍的成年患者中,行或不行抗反流输尿管再植术的单纯膀胱扩大术的有效性和并发症。
我们回顾性分析了 2005 年 7 月至 2016 年 7 月在我院行单纯膀胱扩大术或联合输尿管再植术的 173 例患者的病历。收集了临床资料、磁共振尿路成像和尿动力学参数。采用上尿路扩张和膀胱输尿管反流分级系统评估上尿路功能。评估术后并发症。
160 例患者(266 个输尿管单位)行输尿管再植术,120 个输尿管单位同时行裁剪和/或输尿管松解术。平均随访 44.4 个月(3 至 108 个月)。最大膀胱容量和膀胱顺应性明显增加(p<0.0001),最大逼尿肌压和血清肌酐较术前水平降低(p<0.05)。术后上尿路扩张和膀胱输尿管反流明显改善。术后并发症包括:1 例(0.6%)持续膀胱输尿管反流,14 个输尿管单位(5.3%)吻合口狭窄,11 例(6.4%)肠功能障碍,4 例(2.3%)需剖腹探查,15 例(8.7%)尿路结石和 9 例(5.2%)肾功能恶化。
本回顾性研究表明,伴有抗反流输尿管再植术的单纯膀胱扩大术可能对低压或高级别膀胱输尿管反流、输尿管膀胱连接部梗阻或输尿管迂曲、粘连和/或严重上尿路扩张的患者有益,尤其对病史较长的患者。