Hui Yiang, Elco Christopher P, Heinl Nicole F, Lourenco Ana P, Wiggins Doreen L, Wang Yihong
Department of Pathology, Alpert Medical School of Brown University, Providence, RI, USA.
Department of Diagnostic Imaging, Alpert Medical School of Brown University, Providence, RI, USA.
Breast J. 2018 Mar;24(2):196-198. doi: 10.1111/tbj.12866. Epub 2017 Jul 26.
Diffuse dermal angiomatosis (DDA) is a rare pathologically distinct subtype of reactive angioendotheliomatosis. In the literature, few biopsy-proven cases involving breast skin have been reported. We present a case of a 49-year-old female who presented with an indurated, erythematous, weeping, puckered and tender lesion with focal ulceration. Mammography demonstrated diffuse cutaneous and trabecular thickening concerning for inflammatory breast carcinoma. A punch biopsy demonstrated findings consistent with DDA. To our knowledge, this is the first reported case of DDA mimicking inflammatory carcinoma of the breast by clinical and radiologic examination.
弥漫性皮肤血管瘤病（DDA）是一种罕见的、病理上有明显特征的反应性血管内皮瘤病亚型。在文献中，经活检证实累及乳腺皮肤的病例报道较少。我们报告一例49岁女性，其表现为硬结、红斑、渗液、皱缩且触痛的病变，并伴有局灶性溃疡。乳腺钼靶检查显示弥漫性皮肤和小梁增厚，怀疑为炎性乳腺癌。穿刺活检结果符合弥漫性皮肤血管瘤病。据我们所知，这是首例经临床和影像学检查表现为酷似乳腺炎性癌的弥漫性皮肤血管瘤病病例。
