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一项基于家庭的体育活动干预对乳腺癌幸存者心肺适能的影响;一项随机对照试验。

The effects of a home-based physical activity intervention on cardiorespiratory fitness in breast cancer survivors; a randomised controlled trial.

作者信息

Lahart Ian M, Carmichael Amtul R, Nevill Alan M, Kitas George D, Metsios George S

机构信息

a Faculty of Education, Health and Wellbeing, Institute of Sport , University of Wolverhampton , Walsall , UK.

b Life & Health Sciences, Aston University , Birmingham , UK.

出版信息

J Sports Sci. 2018 May;36(10):1077-1086. doi: 10.1080/02640414.2017.1356025. Epub 2017 Jul 26.

Abstract

The aim of this current randomised controlled trial was to evaluate the effects of a home-based physical activity (PA) intervention on cardiorespiratory fitness in breast cancer survivors. Thirty-two post-adjuvant therapy breast cancer survivors (age = 52 ± 10 years; BMI = 27.2 ± 4.4 kg∙m) were randomised to a six-month home-based PA intervention with face-to-face and telephone PA counselling or usual care. Cardiorespiratory fitness and self-reported PA were assessed at baseline and at six-months. Participants had a mean relative V̇Omax of 25.3 ± 4.7 ml∙kg∙min, which is categorised as "poor" according to age and gender matched normative values. Magnitude-based inference analyses revealed likely at least small beneficial effects (effect sizes ≥.20) on absolute and relative V̇O max (d = .44 and .40, respectively), and total and moderate PA (d = .73 and .59, respectively) in the intervention compared to the usual care group. We found no likely beneficial improvements in any other outcome. Our home-based PA intervention led to likely beneficial, albeit modest, increases in cardiorespiratory fitness and self-reported PA in breast cancer survivors. This intervention has the potential for widespread implementation and adoption, which could considerably impact on post-treatment recovery in this population.

摘要

这项当前的随机对照试验旨在评估居家体育活动(PA)干预对乳腺癌幸存者心肺适能的影响。32名辅助治疗后的乳腺癌幸存者(年龄=52±10岁;体重指数=27.2±4.4kg∙m²)被随机分配至接受为期6个月的居家PA干预组,该干预包括面对面及电话PA咨询,或接受常规护理。在基线期及6个月时评估心肺适能及自我报告的PA情况。参与者的平均相对最大摄氧量(V̇O₂max)为25.3±4.7ml∙kg⁻¹∙min⁻¹,根据年龄和性别匹配的标准值,该数值被归类为“较差”。基于量级的推断分析显示,与常规护理组相比,干预组在绝对和相对V̇O₂max(效应量分别为0.44和0.40)以及总PA和中等强度PA(效应量分别为0.73和0.59)方面可能至少有小的有益效果(效应量≥0.20)。我们未发现其他任何结局有可能的有益改善。我们的居家PA干预使乳腺癌幸存者的心肺适能和自我报告的PA可能出现有益的增加,尽管增幅较小。这种干预措施有广泛实施和采用的潜力,这可能会对该人群的治疗后恢复产生重大影响。

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