Department of Gastrointestinal Surgery, Shaoxing People's Hospital, Shaoxing Hospital of Zhejiang University, Shaoxing, Zhejiang Province, China.
Eur Rev Med Pharmacol Sci. 2017 Jul;21(3 Suppl):27-32.
To study the safety and efficacy of simultaneous completion of colorectal cancer resection and liver metastasis resection by total laparoscopy.
In the observation group, 40 patients with colorectal cancer combined with liver metastasis (CRCLM) were selected to receive total laparoscopic surgery. At the same time, 40 cases were selected for laparoscopic resection of colorectal cancer and hepatic resection as control group.
The outcomes of the two methods in the treatment of CRCLM were compared. The results showed that the difference in surgery time between the two groups was not statistically significant (p>0.05). The blood loss, drainage tube retention time and anal exhaust recovery time in the observation group were significantly less than those in control group (p<0.05). No significant difference in completion rate was found between the two groups (p>0.05); the prevalence rate of complications in the observation group was significantly lower than that in control group (p<0.05). No significant differences in the median survival period and the survival rate at 1 year, 2 years and 3 years after surgery were found between the two groups (p>0.05).
The outcomes of total laparoscopy in the treatment of CRCLM are not inferior to open surgery.
研究完全腹腔镜下同时完成结直肠癌根治术和肝转移灶切除术的安全性和有效性。
观察组中，选择 40 例结直肠癌合并肝转移（CRCLM）患者行完全腹腔镜手术。同时，选择 40 例行腹腔镜结直肠癌切除术和肝切除术的患者作为对照组。
比较两种方法治疗 CRCLM 的效果，结果显示，两组手术时间差异无统计学意义（p＞0.05）；观察组术中出血量、引流管留置时间、肛门排气恢复时间均显著少于对照组（p＜0.05）；两组的根治率无显著差异（p＞0.05）；观察组并发症发生率显著低于对照组（p＜0.05）。两组术后中位生存时间及术后 1 年、2 年、3 年的生存率差异均无统计学意义（p＞0.05）。
完全腹腔镜治疗 CRCLM 的效果并不逊于开腹手术。
