Subramaniam Sathyaseelan, Chao Jennifer H, Chaudhari Pradip
Pediatric Emergency Medicine Fellow, Pediatric Emergency Medicine Department, SUNY Downstate Medical Center/Kings County Hospital Center, New York, NY.
Clinical Assistant Professor, Pediatric Emergency Medicine Department, SUNY Downstate Medical Center/Kings County Hospital Center, New York, NY.
Pediatr Emerg Med Pract. 2016 Nov 22;13(11 Suppl Points & Pearls):S1-S2.
Sickle cell disease is a chronic hematologic disease with a variety of acute, and often recurring, complications. Vaso-occlusive crisis, a unique but common presentation in sickle cell disease, can be challenging to manage. Acute chest syndrome is the leading cause of death in patients with sickle cell disease, occurring in more than half of patients who are hospitalized with a vaso-occlusive crisis. Uncommon diagnoses in children, such as stroke, priapism, and transient red cell aplasia, occur more frequently in patients with sickle cell disease and necessitate a degree of familiarity with the disease process and its management. Patients with sickle cell trait generally have a benign course, but are also subject to serious complications. This issue provides a current review of evidence-based management of the most common acute complications of sickle cell disease seen in pediatric patients in the emergency department. [Points & Pearls is a digest of Pediatric Emergency Medicine Practice].
镰状细胞病是一种慢性血液疾病，伴有多种急性且常反复出现的并发症。血管闭塞性危机是镰状细胞病特有的常见症状，其治疗颇具挑战性。急性胸部综合征是镰状细胞病患者的主要死因，在因血管闭塞性危机住院的患者中，超过半数会出现该症状。儿童中一些不常见的病症，如中风、阴茎异常勃起和短暂性红细胞再生障碍，在镰状细胞病患者中更为频发，这就需要对疾病过程及其管理有一定程度的了解。镰状细胞性状患者通常病情良性，但也可能出现严重并发症。本期专题对急诊科儿科患者中镰状细胞病最常见急性并发症的循证管理进行了综述。[《要点与精华》是儿科急诊医学实践的摘要]
