Cúrdia Gonçalves T, Marinho Carla, Magalhães Joana, Barbosa Mara, Monteiro Sara, Dias de Castro Francisca, Boal Carvalho Pedro, Rosa Bruno, Figueiredo Lília, Cotter José
Departments of aGastroenterology bNutrition and Dietetics, Hospital da Senhora da Oliveira cSchool of Medicine, University of Minho dICVS/3B's, PT Government Associate Laboratory, Braga, Guimarães, Portugal.
Eur J Gastroenterol Hepatol. 2017 Sep;29(9):1097-1101. doi: 10.1097/MEG.0000000000000923.
The real benefit of gastrostomy is still a matter of debate. We aimed to prospectively evaluate the global impact of percutaneous endoscopic gastrostomy (PEG) in patients followed at a specialized multidisciplinary clinic, namely, the impact on the need for healthcare resources, anthropometric measures, pressure ulcers prevention and healing, and nutritional and hydration status.
From the 201 patients who underwent PEG between May 2011 and September 2014, 60 were included in a prospective study. Anthropometric, clinical, and laboratorial variables were collected and compared before and after PEG. Follow-up duration, mortality, and number of emergency department visits or hospital admissions were also assessed.
Thirty-three (55.0%) patients were women and the median age was 79 years. The main indications for PEG were dementia (43.3%) and poststroke dysphagia (30.0%). Four months following PEG, significant decreases in the tricipital skinfold (P=0.002) and brachial perimeter (P=0.003) were found. A decrease in the mean number of hospitalizations (1.4 vs. 0.3; P<0.001) and visits to emergency department (2.2 vs. 1.1; P=0.003) was noted in the next 6 months after PEG compared with the previous semester. In 53.8% of patients with pressure ulcers, complete healing was observed after PEG. PEG was associated with increases in hemoglobin (P=0.024), lymphocytes (P=0.041), cholesterol (P=0.008), transferrin (P<0.001), albumin (P<0.001), and total proteins (P<0.001), and a decrease in serum sodium (P=0.001).
Anthropometric values may not translate the early benefits of a gastrostomy. PEG decreases the need for hospital health care, facilitates healing of pressure ulcers, and induces biochemical changes that may reflect better nutrition and hydration.
胃造口术的真正益处仍存在争议。我们旨在前瞻性评估经皮内镜下胃造口术(PEG)对在一家专业多学科诊所接受随访的患者的整体影响,即对医疗资源需求、人体测量指标、压疮预防和愈合以及营养和水合状态的影响。
在2011年5月至2014年9月期间接受PEG的201例患者中,60例被纳入一项前瞻性研究。收集PEG前后的人体测量、临床和实验室变量并进行比较。还评估了随访时间、死亡率以及急诊科就诊或住院次数。
33例(55.0%)患者为女性,中位年龄为79岁。PEG的主要适应证为痴呆(43.3%)和中风后吞咽困难(30.0%)。PEG后4个月,发现三头肌皮褶厚度(P = 0.002)和臂围(P = 0.003)显著降低。与上一学期相比,PEG后的接下来6个月内,住院平均次数(1.4对0.3;P < 0.001)和急诊科就诊次数(2.2对1.1;P = 0.003)有所减少。在53.8%的压疮患者中,PEG后观察到完全愈合。PEG与血红蛋白(P = 0.024)、淋巴细胞(P = 0.041)、胆固醇(P = 0.008)、转铁蛋白(P < 0.001)、白蛋白(P < 0.001)和总蛋白(P < 0.001)升高以及血清钠降低(P = 0.001)相关。
人体测量值可能无法体现胃造口术的早期益处。PEG减少了医院医疗需求,促进了压疮愈合,并引发了可能反映更好营养和水合状态的生化变化。