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晚期痴呆患者的管饲:负担与感知益处综述

Tube Feeding in Individuals with Advanced Dementia: A Review of Its Burdens and Perceived Benefits.

作者信息

Ijaopo Ezekiel Oluwasayo, Ijaopo Ruth Oluwasolape

机构信息

East Kent Hospital University Foundation Trust, William Harvey Hospital, Ashford, Kent TN24 0LZ, UK.

Royal Stoke University Hospital, Community Haywood Hospital, Stoke-on-Trent ST6 7AG, UK.

出版信息

J Aging Res. 2019 Dec 19;2019:7272067. doi: 10.1155/2019/7272067. eCollection 2019.

DOI:10.1155/2019/7272067
PMID:31929906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6942829/
Abstract

BACKGROUND

Dementia remains a growing concern for societies globally, particularly as people now live longer. About 90% of individuals with advanced dementia suffer from eating problems that lead to general health decline and ultimately impacts upon the physical, psychological, and economic wellbeing of the individuals, caregivers, and the wider society.

OBJECTIVE

To evaluate the burdens and perceived benefits of tube feeding in individuals with advanced dementia.

DESIGN

Narrative review.

METHODS

Computerized databases, including PubMed, Embase, Medline, CINAHL, PsycInfo, and Google Scholar were searched from 2000 to 2019 to identify research papers, originally written in or translated into English language, which investigated oral versus tube feeding outcome in individuals with advanced dementia.

RESULTS

Over 400 articles were retrieved. After quality assessment and careful review of the identified articles, only those that met the inclusion criteria were included for review.

CONCLUSION

Tube feeding neither stops dementia disease progression nor prevents imminent death. Each decision for feeding tube placement in individuals with advanced dementia should be made on a case-by-case basis and involve a multidisciplinary team comprising experienced physicians, nurses, family surrogates, and the relevant allied health professionals. Careful considerations of the benefit-harm ratio should be discussed and checked with surrogate families if they would be consistent with the wishes of the demented person. Further research is required to establish whether tube feeding of individuals with advanced dementia provides more burdens than benefits or vice-versa and evaluate the impacts on quality of life and survival.

摘要

背景

痴呆症仍是全球社会日益关注的问题,尤其是随着人们寿命的延长。约90%的晚期痴呆症患者存在进食问题,这会导致整体健康状况下降,并最终影响患者本人、护理人员及更广泛社会的身体、心理和经济福祉。

目的

评估晚期痴呆症患者鼻饲的负担和感知到的益处。

设计

叙述性综述。

方法

检索2000年至2019年的计算机化数据库,包括PubMed、Embase、Medline、CINAHL、PsycInfo和谷歌学术,以识别最初用英文撰写或翻译成英文的研究论文,这些论文调查了晚期痴呆症患者经口喂养与鼻饲的结果。

结果

检索到400多篇文章。在对识别出的文章进行质量评估和仔细审查后,仅纳入符合纳入标准的文章进行综述。

结论

鼻饲既不能阻止痴呆症疾病进展,也不能预防即将到来的死亡。对于晚期痴呆症患者是否放置鼻饲管的每一项决定都应逐案做出,并应由一个多学科团队参与,该团队包括经验丰富的医生、护士、家庭代理人以及相关的专职医疗专业人员。应讨论并与代理家庭核实对利弊比的仔细考量是否符合痴呆症患者的意愿。需要进一步研究以确定晚期痴呆症患者鼻饲带来的负担是否大于益处,反之亦然,并评估对生活质量和生存的影响。

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J Palliat Med. 2019 Apr;22(4):370-376. doi: 10.1089/jpm.2018.0133. Epub 2018 Nov 9.
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Doctors' Knowledge and Attitudes Regarding Enteral Feeding and Eating Problems in Advanced Dementia.医生对晚期痴呆症患者肠内营养及进食问题的认知与态度。
Dement Geriatr Cogn Dis Extra. 2018 Jul 20;8(2):268-276. doi: 10.1159/000489489. eCollection 2018 May-Aug.
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The outcomes of long term home enteral nutrition (HEN) in older patients with severe dementia.老年重症痴呆患者长期家庭肠内营养(HEN)的结局。
Clin Nutr. 2019 Aug;38(4):1871-1876. doi: 10.1016/j.clnu.2018.07.010. Epub 2018 Jul 20.
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Risk factors for complications and mortality of percutaneous endoscopic gastrostomy insertion.经皮内镜下胃造口术置管并发症及死亡的危险因素。
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Neurocognitive Disorders and Dehydration in Older Patients: Clinical Experience Supports the Hydromolecular Hypothesis of Dementia.老年患者的神经认知障碍与脱水:临床经验支持痴呆的水-分子假说。
Nutrients. 2018 May 3;10(5):562. doi: 10.3390/nu10050562.
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