Chudley Albert E
Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Max Rady College of Medicine, Rady Faculty of Heath Sciences, University of Manitoba, and the Children's Hospital, Winnipeg, MB R3A 1R9, Canada.
Biochem Cell Biol. 2018 Apr;96(2):231-236. doi: 10.1139/bcb-2017-0106. Epub 2017 Jul 26.
This paper discusses the current state of knowledge and practice for diagnosing fetal alcohol spectrum disorder (FASD). The strengths and challenges of different models of diagnosis are compared. Some models require a team approach for evaluation, while other approaches assume that a clinician in his or her office provides a diagnosis based on a review of the patient's medical and social history, behaviour, and physical examination. The author reviews the emergence of new information from recent advances in genetics, imaging, and electrophysiology that has the potential to lead to changes in practice and improved reliability of an FASD diagnosis.
本文讨论了胎儿酒精谱系障碍（FASD）诊断的当前知识状况和实践。比较了不同诊断模型的优势和挑战。一些模型需要团队评估方法，而其他方法则假定临床医生在其办公室根据对患者的医疗和社会病史、行为及体格检查进行回顾后做出诊断。作者回顾了遗传学、影像学和电生理学最新进展中出现的新信息，这些信息有可能导致实践的改变并提高FASD诊断的可靠性。
