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胫骨远端软骨母细胞性骨肉瘤:1例罕见病例报告

Chondroblastic osteosarcoma of the distal tibia: a rare case report.

作者信息

Fredj Aymen Ben, Hassini Lassaad, Fekih Aymen, Allagui Mohamed, Aloui Issam, Abid Abderrazek

机构信息

Department of Orthopaedic Surgery, University Hospital, Monastir, Tunisia.

出版信息

Pan Afr Med J. 2017 May 5;27:11. doi: 10.11604/pamj.2017.27.11.12418. eCollection 2017.

Abstract

Chondroblastic osteosarcoma, representing about 25% of osteosarcoma, is a fatal primary malignancy of the skeleton if not diagnosed and treated appropriately. It most commonly occurs in the long bones of the extremities near the metaphyseal growth plates. In this report, we describe the occurrence of chondroblastic osteosarcoma involving the left distal tibia in a 14-year-old male. The diagnosis was confirmed by the histological examination of a surgical biopsy. The patient was treated by both surgery and neoadjuvant chemotherapy. No recurrence was noted at 3 years of follow-up. To our knowledge, only two cases describing chondroblastic osteosarcoma of the distal tibia had been reported through English medical literature. Therefore, the aim of our article is to make the clinician aware of this rare clinical presentation and also to provide a comprehensive review of the literature related to this uncommon malignant tumour.

摘要

软骨母细胞性骨肉瘤约占骨肉瘤的25%,如果未得到恰当的诊断和治疗,它是一种致命的原发性骨骼恶性肿瘤。它最常发生于四肢长骨靠近干骺端生长板的部位。在本报告中,我们描述了一名14岁男性发生于左胫骨远端的软骨母细胞性骨肉瘤。通过手术活检的组织学检查确诊。患者接受了手术和新辅助化疗。随访3年未发现复发。据我们所知,通过英文医学文献仅报道过2例关于胫骨远端软骨母细胞性骨肉瘤的病例。因此,我们本文的目的是让临床医生了解这种罕见的临床表现,并对与这种罕见恶性肿瘤相关的文献进行全面综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc29/5511719/d46ec5c9a3f0/PAMJ-27-11-g001.jpg

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