Ono Masateru
School of Agriculture, Tokai University, 9-1-1 Toroku, Higashi-ku, Kumamoto, 862-8652, Japan.
J Nat Med. 2017 Oct;71(4):591-604. doi: 10.1007/s11418-017-1114-5. Epub 2017 Jul 26.
Resin glycosides are well known as purgative ingredients, which are characteristic of certain crude drugs such as Mexican Scammony Radix, Orizabae Tuber, and Jalapae Tuber, all of which originate from Convolvulaceae plants. Depending on their solubility in ether, these are roughly classified into two groups-jalapin (soluble) and convolvulin (insoluble). Almost all jalapins hitherto isolated and characterized had common intramolecular macrocyclic ester structures. These are composed of 1 mol of oligoglycoside of hydroxyl fatty acid (glycosidic acid) partially acylated by some organic acids at the sugar moiety, some examples of which are ester-type dimers. On the other hand, convolvulin is regarded as an oligomer of a variety of acylated glycosidic acids. This review describes the isolation and structural elucidation of resin glycosides from some Convolvulaceae plants, including Ipomoea operculata, Pharbitis nil, Quamoclit pennata, Calystegia soldanella, and I. muricata.
树脂糖苷作为泻下成分而广为人知，它们是某些生药的特征成分，如墨西哥药旋花根、紫茉莉块茎和药喇叭块茎，这些生药均源自旋花科植物。根据它们在乙醚中的溶解性，大致可分为两类——药喇叭脂苷（可溶）和旋花脂苷（不溶）。迄今为止，几乎所有已分离和鉴定的药喇叭脂苷都具有共同的分子内大环酯结构。它们由1摩尔羟基脂肪酸的低聚糖苷（糖苷酸）组成，其糖部分被一些有机酸部分酰化，其中一些例子是酯型二聚体。另一方面，旋花脂苷被认为是多种酰化糖苷酸的低聚物。本综述描述了从一些旋花科植物中分离树脂糖苷并阐明其结构的过程，这些植物包括圆叶牵牛、裂叶牵牛、五爪金龙、滨旋花和刺毛牵牛。
