鉴定新型猿猴内源性逆转录病毒，这些病毒在当前猿猴逆转录病毒（SRV）诊断检测中与猿猴逆转录病毒（SRV）无法区分。
Identification of novel simian endogenous retroviruses that are indistinguishable from simian retrovirus (SRV) on current SRV diagnostic assays.
作者信息
Grant Richard, Keele Brandon, Kuller LaRene, Watanabe Robin, Perret Alex, Smedley Jeremy
机构信息
Washington National Primate Research Center, University of Washington, Seattle, WA, USA.
AIDS and Cancer Virus Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
出版信息
J Med Primatol. 2017 Aug;46(4):158-161. doi: 10.1111/jmp.12297.
Simian betaretroviruses include the well-known exogenous simian retroviruses (SRV-1 through SRV-8), and some closely related simian endogenous retroviruses (SERV). Here, we characterized two new viral genomes, which appear to represent novel SERVs but have characteristics of both SRV and SERV highlighting the need to develop new assays providing molecular and serologic differentiation of SERV and SRV to avoid false positives.
猿猴β逆转录病毒包括著名的外源性猿猴逆转录病毒（SRV-1至SRV-8），以及一些密切相关的猿猴内源性逆转录病毒（SERV）。在此，我们对两个新的病毒基因组进行了特征分析，它们似乎代表了新型SERV，但同时具有SRV和SERV的特征，这突出表明需要开发新的检测方法，以实现SERV和SRV的分子和血清学鉴别，从而避免假阳性。
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