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用于剂量学应用的儿科头部体素模型数据库的开发。

Development of a paediatric head voxel model database for dosimetric applications.

作者信息

Stratis Andreas, Touyz Nathan, Zhang Guozhi, Jacobs Reinhilde, Bogaerts Ria, Bosmans Hilde

机构信息

1 Department of Imaging and Pathology, Katholieke Universiteit Leuven, Leuven, Belgium.

2 Department of Radiology, University Hospitals of Leuven, Leuven, Belgium.

出版信息

Br J Radiol. 2017 Oct;90(1078):20170051. doi: 10.1259/bjr.20170051. Epub 2017 Jul 27.

Abstract

OBJECTIVE

To develop a database of paediatric head voxel models intended for Monte Carlo (MC) dosimetric applications.

METHODS

Seventeen head and neck CT image data sets were retrieved from the picture archiving and communicating system of our hospital and were reformed into voxel models. 22 organs were segmented at each data set. The segmented organ masses were compared to the respective age- and gender-specific ICRP reference mass value. Adjustments were made such that segmented and reference mass values coincide within a tolerance of 10%. A dental cone beam CT cleft palate simulation study was set up to demonstrate the applicability of our database to MC frameworks and to investigate the need for age- and gender-specific paediatric models.

RESULTS

The designed database covers the age range from 2 months to 14 years old. Each model represents a reference head voxel phantom for its corresponding age and gender category. The simulation study revealed absorbed organ dose differences larger than 50% among the 5, 8 and 12 years old models when exposed to identical conditions.

CONCLUSION

Children cannot be represented by one average phantom covering the entire age range like adults due to the fact that their organs change rapidly in size and shape. A database of paediatric head voxel models was designed to enable dose calculations via MC simulations. Advances in knowledge: The application of each model of the database to MC frameworks provides age- and gender-specific organ dose estimations from medical exposures in the head and neck region.

摘要

目的

开发一个用于蒙特卡罗(MC)剂量学应用的儿科头部体素模型数据库。

方法

从我院图像存档与通信系统中检索了17例头颈部CT图像数据集,并将其重建为体素模型。在每个数据集中对22个器官进行了分割。将分割后的器官质量与相应年龄和性别的国际辐射防护委员会(ICRP)参考质量值进行比较。进行了调整,以使分割后的质量值与参考质量值在10%的公差范围内一致。开展了一项牙科锥形束CT腭裂模拟研究,以证明我们的数据库对MC框架的适用性,并研究是否需要针对年龄和性别的儿科模型。

结果

所设计的数据库涵盖了2个月至14岁的年龄范围。每个模型代表其相应年龄和性别类别的参考头部体素模型。模拟研究表明,在相同条件下,5岁、8岁和12岁模型之间的器官吸收剂量差异大于50%。

结论

由于儿童器官的大小和形状变化迅速,不能像成人那样用一个覆盖整个年龄范围的平均模型来代表儿童。设计了一个儿科头部体素模型数据库,以便通过MC模拟进行剂量计算。知识进展:将数据库中的每个模型应用于MC框架,可对头颈部区域医疗照射进行年龄和性别特异性器官剂量估计。

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