Cartwright K A, Stuart J M, Noah N D
Lancet. 1986 Sep 6;2(8506):558-61. doi: 10.1016/s0140-6736(86)90124-8.
Between October, 1981, and March, 1986, there were 65 cases of meningococcal infection, about five times the expected number, in Gloucester Health District. The cases, mainly in teenagers and young adults, were clustered in the Stroud district and in the southern part of Gloucester City, and most were caused by a sulphonamide-resistant group B type 15 meningococcus. 2 patients died. Only 57% of meningitis cases were formally notified. 7 (11%) patients had septicaemia without meningitis, not a notifiable disease. All meningococcal disease should be made notifiable and meningococci should be serotyped routinely so that the epidemiology of the disease can be monitored before the introduction of suitable vaccines.
1981年10月至1986年3月期间,格洛斯特健康区发生了65例脑膜炎球菌感染病例,约为预期数量的五倍。这些病例主要发生在青少年和年轻人中,集中在斯特劳德区和格洛斯特市南部,大多数是由耐磺胺的B群15型脑膜炎球菌引起的。2名患者死亡。只有57%的脑膜炎病例得到了正式通报。7名(11%)患者患有无脑膜炎的败血症,这不是应通报的疾病。所有脑膜炎球菌病都应予以通报,并且应对脑膜炎球菌进行常规血清分型,以便在引入合适疫苗之前对该病的流行病学进行监测。