Wu Li-Tzy, McNeely Jennifer, Subramaniam Geetha A, Brady Kathleen T, Sharma Gaurav, VanVeldhuisen Paul, Zhu He, Schwartz Robert P
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA; Department of Medicine, Division of General Internal Medicine, Duke University Medical Center, Durham, NC, USA; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA; Center for Child and Family Policy, Sanford School of Public Policy, Duke University, Durham, NC, USA.
Department of Population Health, New York University School of Medicine, New York, NY, USA.
Drug Alcohol Depend. 2017 Oct 1;179:42-46. doi: 10.1016/j.drugalcdep.2017.05.048. Epub 2017 Jul 13.
There are limited data about the extent of DSM-5 substance use disorders (SUDs) among primary care patients.
This study analyzed data from a multisite validation study of a substance use screening instrument conducted in a diverse sample of 2000 adults aged ≥18 years recruited from five primary care practices in four states. Prevalence and correlates of 12-month DSM-5 SUDs were examined.
Overall, 75.5% of the sample used any substance, including alcohol (62.0%), tobacco (44.1%), or illicit drugs/nonmedical medications (27.9%) in the past 12 months (marijuana 20.8%, cocaine 7.3%, opioids 4.8%, sedatives 4.1%, heroin 3.9%). The prevalence of any 12-month SUD was 36.0% (mild disorder 14.2%, moderate/severe disorder 21.8%): tobacco 25.3% (mild 11.5%, moderate/severe 13.8%); alcohol 13.9% (mild 6.9%, moderate/severe 7.0%); and any illicit/nonmedical drug 14.0% (mild 4.0%, moderate/severe 10.0%). Among past 12-month users, a high proportion of tobacco or drug users met criteria for a disorder: tobacco use disorder 57.4% (26.1% mild, 31.3% moderate/severe) and any drug use disorder 50.2% (14.3% mild, 35.8% moderate/severe); a lower proportion of alcohol users (22.4%) met criteria for alcohol use disorder (11.1% mild, 11.3% moderate/severe). Over 80% of adults with opioid/heroin use disorder met criteria for a moderate/severe disorder. Younger ages, male sex, and low education were associated with increased odds of having SUD.
These findings reveal the high prevalence of SUDs in primary care and underscore the need to identify and address them.
关于初级保健患者中符合《精神疾病诊断与统计手册》第5版(DSM - 5)物质使用障碍(SUDs)的程度的数据有限。
本研究分析了一项物质使用筛查工具的多地点验证研究的数据,该研究在从四个州的五个初级保健机构招募的2000名年龄≥18岁的成年人的多样化样本中进行。检查了12个月内符合DSM - 5物质使用障碍的患病率及其相关因素。
总体而言,75.5%的样本在过去12个月内使用过任何物质,包括酒精(62.0%)、烟草(44.1%)或非法药物/非医疗用途药物(27.9%)(大麻20.8%、可卡因7.3%、阿片类药物4.8%、镇静剂4.1%、海洛因3.9%)。任何12个月内物质使用障碍的患病率为36.0%(轻度障碍14.2%,中度/重度障碍21.8%):烟草25.3%(轻度11.5%,中度/重度13.8%);酒精13.9%(轻度6.9%,中度/重度7.0%);以及任何非法/非医疗药物14.0%(轻度4.0%,中度/重度10.0%)。在过去12个月的使用者中,很大一部分烟草或药物使用者符合障碍标准:烟草使用障碍57.4%(轻度26.1%,中度/重度31.3%),任何药物使用障碍50.2%(轻度14.3%,中度/重度35.8%);符合酒精使用障碍标准的酒精使用者比例较低(22.4%)(轻度11.1%,中度/重度11.3%)。超过80%的阿片类药物/海洛因使用障碍成年人符合中度/重度障碍标准。年龄较小、男性和低教育程度与物质使用障碍的患病几率增加相关。
这些发现揭示了初级保健中物质使用障碍的高患病率,并强调了识别和解决这些问题的必要性。