Fröhlich H
Wien Med Wochenschr. 1986 Jun 30;136(11-12):260-3.
We know close to nothing why preterm or adterm delivery in human being starts. Either it is the breakdown of mechanisms protecting the pregnancy when it is time for the baby to flee the no more adequate surrounding of the uterus, or the activation of substances starting uterine contractions. Most probable is the interaction between oxytocin and prostaglandines which leads to the onset of labour; the influence of the fetus on this procedure is discussed. Stimulation of contractions: Oxytocin given as infusion with or without foregoing priming by locally applied prostaglandines (exact supervision of uterine motility and the well-being of the fetus by CTG) and/or amniotomy. Infusions of Prostaglandines always cause uterine contractions ending with the expulsion of the fetus. Inhibition of uterine contractility: In cases of threatening premature delivery before during and after intraabdominal operations and fetal distress during term delivery nowadays Betamimetics are given. The application of alcohol is reserved for special cases.
我们几乎不知道人类早产或足月分娩为何开始。要么是当胎儿到了该逃离不再适宜的子宫环境时，保护妊娠的机制出现故障，要么是引发子宫收缩的物质被激活。最有可能的是催产素与前列腺素之间的相互作用导致分娩开始；文中讨论了胎儿对这一过程的影响。宫缩刺激：通过静脉输注催产素，可在局部应用前列腺素进行或不进行预激（通过产时胎心监护精确监测子宫活动及胎儿健康状况）和/或人工破膜。输注前列腺素总会引发子宫收缩，直至胎儿娩出。子宫收缩抑制：如今，在腹腔手术期间及术后有早产风险以及足月分娩时出现胎儿窘迫的情况下，会使用β-拟交感神经药。酒精的应用则留作特殊情况。
