袖状胃切除术 8 年后的长期结果如何?
What are the long-term results 8 years after sleeve gastrectomy?
机构信息
The American Surgecenter, Abu Dhabi, United Arab Emirates.
Centre Chirurgical de l'Obesite, Clinique Saint Michel, Toulon, France; Centre Hospitalier Universitaire Montpellier, Montpellier, France.
出版信息
Surg Obes Relat Dis. 2017 Jul;13(7):1110-1115. doi: 10.1016/j.soard.2017.03.007. Epub 2017 Mar 23.
BACKGROUND
Laparoscopic sleeve gastrectomy (LSG) became the most frequent bariatric procedure performed in France (2011) and in the United States (2013), but studies reporting long-term results are still rare.
SETTING
Private hospital, France.
METHODS
This is a retrospective analysis of a prospective cohort of 168 patients who underwent LSG between 2005 and 2008. The objective of this study was to present the 8-year outcome concerning weight loss, modification of co-morbidities, and to report the revisional surgery after sleeve.
RESULTS
The preoperative mean body mass index was 42.8 kg/m2 (31.1-77.9), 35 patients were super obese, and 64 patients had a previous gastric band. For LSG as a definitive bariatric procedure, 8 years of follow-up data were available for 116 patients (follow-up: 69%). Of the remainder, 23 patients underwent revisional surgery and 29 were lost to follow-up. For the entire cohort, the mean excess weight loss (EWL) was 76% (0-149) at 5 years and 67% (4-135) at 8 years, respectively. Of the 116 patients with 8 years of follow-up, 82 patients had>50% EWL at 8 years (70.7%). Percentages of co-morbidities resolved were hypertension, 59.4%; type 2 diabetes, 43.4%; and obstructive sleep apnea, 72.4%. Twenty-three patients had revisional surgery for weight regain (n = 14) or for severe reflux (n = 9) at a mean period of 50 months (9-96). Twelve patients underwent resleeve gastrectomy, 6 patients underwent conversion to a bypass, and 5 patients to duodenal switch (1 single anastomosis duodeno-ileostomy). A total of 31% of patients reported gastroesophageal reflux symptoms at 8 years.
CONCLUSIONS
At 8 years postoperatively, the LSG as a definitive bariatric procedure remained effective for 59% of cases. The results appear to be more favorable especially for the non-super-obese patients and primary procedures. LSG is a well-tolerated bariatric procedure with low long-term complication rates.
背景
腹腔镜袖状胃切除术(LSG)已成为法国(2011 年)和美国(2013 年)最常见的减重手术,但仍缺乏长期结果的研究报告。
地点
法国私人医院。
方法
这是对 2005 年至 2008 年间接受 LSG 的 168 例患者进行的前瞻性队列的回顾性分析。本研究的目的是介绍 8 年的减重效果、合并症的改善情况,并报告袖套切除后的修正手术。
结果
术前平均体重指数为 42.8kg/m2(31.1-77.9),35 例患者为超级肥胖,64 例患者曾行胃带术。对于 LSG 作为确定性减重手术,116 例患者可获得 8 年随访数据(随访率:69%)。其余 23 例患者接受了修正手术,29 例患者失访。对于整个队列,5 年时平均超重减轻率(EWL)为 76%(0-149),8 年时为 67%(4-135)。在 116 例 8 年随访患者中,82 例患者 8 年时 EWL 大于 50%(70.7%)。高血压、2 型糖尿病和阻塞性睡眠呼吸暂停缓解率分别为 59.4%、43.4%和 72.4%。23 例患者因体重反弹(n=14)或严重反流(n=9)行修正手术,平均间隔 50 个月(9-96)。12 例患者行再袖状胃切除术,6 例患者行旁路转换术,5 例患者行十二指肠转位术(1 例单吻合口空肠回肠吻合术)。8 年后,31%的患者报告有胃食管反流症状。
结论
作为确定性减重手术,LSG 术后 8 年仍有效,59%的患者有效。结果似乎更有利,尤其是对非超级肥胖患者和初次手术患者。LSG 是一种耐受性良好的减重手术,长期并发症发生率低。