College of Medicine, Department of Surgery, King Saud University, Riyadh, Saudi Arabia.
Dr. Sulaiman Alhabib Hospital, Riyadh, Saudi Arabia.
Obes Surg. 2024 May;34(5):1630-1638. doi: 10.1007/s11695-024-07160-1. Epub 2024 Mar 14.
Controversy regarding the timing of pregnancy and its implications is present in the literature.
To evaluate the midterm outcome of weight loss in women who have undergone laparoscopic sleeve gastrectomy (LSG) followed by pregnancy at two different times.
We retrospectively reviewed 53 women who matched the inclusion criteria and included them in the analysis. Demographics and anthropometric measurements were collected. Women who conceived within 12 months of LSG were labeled as early group (EG), and who conceived after 12 months were noted as late group (LG).
There were no differences between the groups regarding obesity-associated disease and number of pregnancies before. EG had higher weight (P = 0.0001) and body mass index (BMI) (P = 0.002) at LSG. The mean interval time for EG was 6.7 ± 3.2 months, and LG was 20 ± 5.2 months. Gestational weight gain (GWG) was lower in the EG (P = 0.001). There were no differences in the number of small for gestational age (SGA) births or gestational weight. In the first 2 years after LSG, LG had a higher percentage of total weight loss (%TWL) and percentage of body mass index loss (%EBMIL) (P < 0.0001). After 5 years of follow-up, %TWL (P = 0.4) and %EBMIL (P = 0.1) were not statistically significant between both groups.
Conception within 12 months from LSG might hinder the weight loss process in the short term but have no significant effect over 5 years of follow-up.
关于妊娠时机及其影响的争议在文献中存在。
评估腹腔镜袖状胃切除术（LSG）后不同时间怀孕对女性中期结局的影响。
我们回顾性分析了符合纳入标准的 53 名女性，并将其纳入分析。收集了人口统计学和人体测量学数据。在 LSG 后 12 个月内怀孕的女性被标记为早期组（EG），12 个月后怀孕的女性被标记为晚期组（LG）。
两组在肥胖相关疾病和之前的妊娠次数方面无差异。EG 在 LSG 时体重（P = 0.0001）和体重指数（BMI）（P = 0.002）更高。EG 的平均间隔时间为 6.7 ± 3.2 个月，LG 为 20 ± 5.2 个月。EG 的妊娠体重增加（GWG）较低（P = 0.001）。两组的小于胎龄儿（SGA）出生率或妊娠体重无差异。在 LSG 后 2 年内，LG 的总体重减轻百分比（%TWL）和体重指数减轻百分比（%EBMIL）更高（P < 0.0001）。随访 5 年后，两组之间%TWL（P = 0.4）和%EBMIL（P = 0.1）均无统计学差异。
LSG 后 12 个月内怀孕可能会在短期内阻碍体重减轻过程，但在 5 年的随访中无显著影响。
