Gaut D, Cone B D, Gregson A L, Agopian V G
Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
Deparment of Pathology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.
Transplant Proc. 2017 Sep;49(7):1608-1614. doi: 10.1016/j.transproceed.2017.03.074. Epub 2017 Jul 26.
Mucormycosis has emerged as a major threat to transplant recipients with high morbidity and mortality. This infection most commonly presents with rhino-sino-orbital localization. Gastrointestinal mucormycosis is uncommon, with presenting symptoms usually abdominal in nature. Here, we describe the case of a liver transplant recipient who developed gastrointestinal mucormycosis with an initial manifestation of femoral nerve palsy, ultimately resulting in fungal dissemination and patient demise. This case highlights the challenges in making a timely diagnosis of mucormycosis, particularly in immunocompromised patients.
毛霉菌病已成为对移植受者构成重大威胁的疾病，其发病率和死亡率都很高。这种感染最常见于鼻-鼻窦-眼眶部位。胃肠道毛霉菌病并不常见，其症状通常以腹部症状为主。在此，我们描述了一例肝移植受者发生胃肠道毛霉菌病的病例，该患者最初表现为股神经麻痹，最终导致真菌播散和患者死亡。该病例凸显了及时诊断毛霉菌病的挑战，尤其是在免疫功能低下的患者中。
