与金刚烷胺相关的精神分裂症恶化
Exacerbation of schizophrenia associated with amantadine.
作者信息
Nestelbaum Z, Siris S G, Rifkin A, Klar H, Reardon G T
出版信息
Am J Psychiatry. 1986 Sep;143(9):1170-1. doi: 10.1176/ajp.143.9.1170.
PMID:2875665
Abstract
Administration of amantadine was associated with psychotic decompensations in two schizophrenic patients being maintained on concomitant neuroleptic medication. Despite a postulated dopaminergic mechanism, there seems to have been only one previous report of amantadine's precipitating psychosis in a schizophrenic patient.
摘要
在两名正在接受抗精神病药物联合治疗的精神分裂症患者中，金刚烷胺的使用与精神错乱有关。尽管推测其作用机制与多巴胺能有关，但此前似乎仅有一份关于金刚烷胺诱发精神分裂症患者精神病发作的报告。
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