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散发性多发性内分泌肿瘤与肩胛部异位乳腺并存。是巧合还是存在生物学关联?

Coexistence of sporadic multiple endocrine neoplasia and scapular ectopic breast. Coincidence or biologically associated?

作者信息

Cohen N, Modai D, Pik A, Golik A, Weissgarten J, Segal M

出版信息

Arch Intern Med. 1986 Sep;146(9):1822-3.

PMID:2875696
Abstract

We describe a patient who presented with sporadic pheochromocytoma and parathyroid adenoma in the absence of medullary thyroid carcinoma, which coexisted with fully developed scapular ectopic breast tissue. If not coincidental, this association might support the concept that all components of multiple endocrine neoplasia type IIA originate from embryonic ectodermal tissue, and that sporadic multiple endocrine neoplasia type IIA, as well as ectopic breast tissue, may result from a noxious event at a critical embryonic stage.

摘要

我们描述了一名患者,其患有散发性嗜铬细胞瘤和甲状旁腺腺瘤,无甲状腺髓样癌,且同时存在完全发育的肩胛部异位乳腺组织。若非巧合,这种关联可能支持以下观点:IIA型多发性内分泌腺瘤病的所有组分均起源于胚胎外胚层组织,散发性IIA型多发性内分泌腺瘤病以及异位乳腺组织可能是由关键胚胎期的有害事件所致。

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