King B F, Workman C H, Latham R A
Cleft Palate J. 1979 Jul;16(3):223-9.
An anatomical reconstruction of the protruded premaxillary segment of an infant with bilateral cleft of the primary palate was made from serial histological sections and described in comparison with reconstruction columella, alar cartilages, nasal septum, and premaxillae of a neonatal control specimen. Most of the bilateral cleft abnormality was seen in the premaxillary bones which were advanced on the nasal septum and whose alveolar process protuded anteriorly into the columellar area. The medial crura of the alar cartilages and the nasal septum in the cleft specimen showed an essentially normal structure. Underdevelopment of the columbella was considered as primarily failure in the development of columellar skin caused by the invasive obstruction by the premaxillary bones.
通过连续组织学切片对一名患有原发性腭裂双侧裂隙婴儿的突出前颌段进行了解剖重建，并与新生儿对照标本的重建小柱、鼻翼软骨、鼻中隔和前颌骨进行比较描述。双侧裂隙异常大多见于前颌骨，其在鼻中隔上向前移位，牙槽突向前突入小柱区域。裂隙标本中鼻翼软骨的内侧脚和鼻中隔显示结构基本正常。小柱发育不全被认为主要是由于前颌骨的侵入性阻塞导致小柱皮肤发育失败。
