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Baseline Parameters in Clinical Trials for Nonalcoholic Steatohepatitis: Recommendations From the Liver Forum.

作者信息

Patel Yuval A, Imperial Joanne C, Muir Andrew J, Anstee Quentin M, DeBrota David, Dimick-Santos Lara, Filozof Claudia, Mehta Ruby, Sanyal Arun J, Schabel Elmer, Neuschwander-Tetri Brent A, Miller Veronica

机构信息

Duke University School of Medicine, Durham, North Carolina.

Conatus Pharmaceuticals, San Diego, California.

出版信息

Gastroenterology. 2017 Sep;153(3):621-625.e7. doi: 10.1053/j.gastro.2017.07.024. Epub 2017 Jul 27.

DOI:10.1053/j.gastro.2017.07.024
PMID:28757264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5861348/
Abstract
摘要

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本文引用的文献

1
Case definitions for inclusion and analysis of endpoints in clinical trials for nonalcoholic steatohepatitis through the lens of regulatory science.非酒精性脂肪性肝炎临床试验终点纳入和分析的定义：从监管科学的角度。
Hepatology. 2018 May;67(5):2001-2012. doi: 10.1002/hep.29607. Epub 2018 Feb 22.
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Nonalcoholic fatty liver disease.非酒精性脂肪性肝病。
Nat Rev Dis Primers. 2015 Dec 17;1:15080. doi: 10.1038/nrdp.2015.80.
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Genetic Factors That Affect Risk of Alcoholic and Nonalcoholic Fatty Liver Disease.遗传因素对酒精性和非酒精性脂肪性肝病风险的影响。
Gastroenterology. 2016 Jun;150(8):1728-1744.e7. doi: 10.1053/j.gastro.2016.01.037. Epub 2016 Feb 10.
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Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes.全球非酒精性脂肪性肝病流行病学——患病率、发病率和结局的荟萃分析评估。
Hepatology. 2016 Jul;64(1):73-84. doi: 10.1002/hep.28431. Epub 2016 Feb 22.
5
Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease.肝纤维化而非其他组织学特征与非酒精性脂肪性肝病患者的长期预后相关。
Gastroenterology. 2015 Aug;149(2):389-97.e10. doi: 10.1053/j.gastro.2015.04.043. Epub 2015 Apr 29.
6
Bariatric Surgery and Non-Alcoholic Fatty Liver Disease: a Systematic Review of Liver Biochemistry and Histology.减重手术与非酒精性脂肪性肝病：肝脏生物化学与组织学的系统评价
Obes Surg. 2015 Dec;25(12):2280-9. doi: 10.1007/s11695-015-1691-x.
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Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop.非酒精性脂肪性肝炎药物及生物标志物开发中的挑战与机遇：美国肝病研究协会-美国食品药品监督管理局联合研讨会的结果与建议
Hepatology. 2015 Apr;61(4):1392-405. doi: 10.1002/hep.27678. Epub 2015 Mar 19.
8
Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: implications for prognosis and clinical management.使用配对活检评估非酒精性脂肪性肝病从脂肪变性进展为纤维性脂肪性肝炎的证据：对预后和临床管理的影响。
J Hepatol. 2015 May;62(5):1148-55. doi: 10.1016/j.jhep.2014.11.034. Epub 2014 Dec 1.
9
Utility and appropriateness of the fatty liver inhibition of progression (FLIP) algorithm and steatosis, activity, and fibrosis (SAF) score in the evaluation of biopsies of nonalcoholic fatty liver disease.非酒精性脂肪性肝病肝活检评估中脂肪肝进展抑制（FLIP）算法和脂肪变性、活动度和纤维化（SAF）评分的效用和适宜性。
Hepatology. 2014 Aug;60(2):565-75. doi: 10.1002/hep.27173. Epub 2014 Jun 26.
10
Prevalence of nonalcoholic fatty liver disease in the United States: the Third National Health and Nutrition Examination Survey, 1988-1994.非酒精性脂肪性肝病在美国的流行情况：第三次国家健康和营养检查调查，1988-1994 年。
Am J Epidemiol. 2013 Jul 1;178(1):38-45. doi: 10.1093/aje/kws448. Epub 2013 May 23.