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泌尿生殖系结核病的临床下形式在肺结核患者中的发生率。

The incidence of subclinical forms of urogenital tuberculosis in patients with pulmonary tuberculosis.

机构信息

Department of Urology, Thomayer Hospital, Videnska 800, 140 59 Prague 4, Czech Republic; Department of Urology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic; Department of Urology, 3rd Faculty of Medicine of Charles University and University Hospital, Kralovske Vinohrady, Srobarova 1150/50, 100 34 Prague 10, Czech Republic.

Department of Urology, 3rd Faculty of Medicine of Charles University and University Hospital, Kralovske Vinohrady, Srobarova 1150/50, 100 34 Prague 10, Czech Republic.

出版信息

J Infect Public Health. 2018 Mar-Apr;11(2):243-245. doi: 10.1016/j.jiph.2017.07.005. Epub 2017 Jul 27.

Abstract

The aim of our study was to determine whether patients with pulmonary tuberculosis may have subclinical forms of urogenital tuberculosis. Between 2011 and 2012, a prospective study was conducted. Basic demographic parameters were recorded and the following investigations were performed: direct bacilloscopy of sputum, evaluation of affected lung fields and presence of cavities on chest X-ray, Mantoux tuberculin skin test II, and interferon gamma release assay. Culture and molecular methods for Mycobacterium tuberculosis in urine were performed. In cases with a positive urine test, an ultrasound examination, computed tomography scan of the abdomen, and endoscopy of the urinary tract were performed. A total of 102 patients (75 men and 27 women) were included in the study, with a median age of 46.8 years. Subclinical forms of urogenital TB were detected in 7 patients; 5 by molecular methods, 1 by urine culture, and 1 with both methods The presence of subclinical forms of genitourinary TB was found in 4 patients without and 3 patients with findings on imaging methods corresponding to TB. A significant number of patients with pulmonary tuberculosis may simultaneously have subclinical forms of urogenital TB.

摘要

我们的研究目的是确定肺结核患者是否可能存在泌尿生殖系统结核的亚临床形式。在 2011 年至 2012 年期间进行了一项前瞻性研究。记录了基本的人口统计学参数,并进行了以下检查:痰直接细菌镜检、胸部 X 射线评估受影响的肺野和空洞的存在、曼托斯结核菌素皮肤试验 II 和干扰素γ释放测定。对尿液中的结核分枝杆菌进行培养和分子检测。在尿液检测阳性的情况下,进行了超声检查、腹部计算机断层扫描和泌尿道内镜检查。共有 102 名患者(75 名男性和 27 名女性)纳入研究,中位年龄为 46.8 岁。在 7 名患者中发现了泌尿生殖系统结核的亚临床形式;5 名通过分子方法,1 名通过尿液培养,1 名通过两种方法。在 4 名未发现影像学方法与结核对应的患者和 3 名影像学方法与结核对应的患者中发现了泌尿生殖系统结核的亚临床形式。大量肺结核患者可能同时存在泌尿生殖系统结核的亚临床形式。

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