慢性、不愈合糖尿病足溃疡中发生的鳞状细胞癌
Squamous Cell Carcinoma Arising in a Chronic, Nonhealing Diabetic Foot Ulcer.
作者信息
Larijani Bagher, Tavangar Seyed Mohammad, Bandarian Fatemeh
机构信息
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences.
出版信息
Wounds. 2017 Jul;29(7):E48-E50.
UNLABELLED
Diabetic foot ulcers (DFUs) are a severe and costly complication of diabetes and may result in foot amputation.
CASE REPORT
A 69-year-old man with a 10-year history of type 2 diabetes, who was undergoing routine care for diabetes in the authors' clinic, developed a DFU of his right foot of 4 years' duration. The wound did not respond to conventional treatments, and imaging studies were normal. His 2 biopsies tested negative for malignancy. The DFU was fully removed surgically. Following surgical removal, squamous cell carcinoma (SCC) was diagnosed in the histologic study of the wound.
CONCLUSION
Clinicians should consider a diagnosis of SCC in any chronic, nonhealing DFU. Early surgical resection of a chronic, nonhealing DFU may prevent development of SCC in an ulcer.
未标注
糖尿病足溃疡（DFUs）是糖尿病的一种严重且代价高昂的并发症，可能导致足部截肢。
病例报告
一名69岁男性，有2型糖尿病病史10年，在作者所在诊所接受糖尿病常规治疗时，右脚出现了持续4年的糖尿病足溃疡。伤口对传统治疗无反应，影像学检查正常。他的两次活检结果均为恶性阴性。糖尿病足溃疡通过手术完全切除。手术切除后，在伤口的组织学研究中诊断出鳞状细胞癌（SCC）。
结论
临床医生应考虑对任何慢性、不愈合的糖尿病足溃疡进行鳞状细胞癌的诊断。对慢性、不愈合的糖尿病足溃疡进行早期手术切除可能预防溃疡中鳞状细胞癌的发生。
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