Management of solitary fibrous tumors localized in extremity: case series and a review of the literature.

OBJECTIVES

This study aims to evaluate the clinical characteristics and treatment results of patients with a diagnosis of solitary fibrous tumor localized in extremity.

PATIENTS AND METHODS

Clinical findings, treatment methods, clinical outcomes and treatment failures of seven patients (3 males, 4 females; mean age 49.7±20.7 years; range 22 to 79 years) diagnosed as solitary fibrous tumor localized in extremity between January 2005 and December 2016 were evaluated retrospectively.

RESULTS

Most frequent localization was the thigh (42.8%, n=3). Mean tumor size was 10.8±2.4 cm (range 8-15 cm). All patients applied with painless mass and all had primary tumor. All patients had localized disease at the time of diagnosis. Postoperative mean follow-up duration was 44.4 months (range 13-121 months). Marginal resection was performed in two patients at low risk group while wide resection was performed in other patients at moderate and high risk groups. Patients who underwent marginal resection were performed adjuvant radiotherapy. No recurrence or metastasis was detected in any of the patients during follow-up.

CONCLUSION

In the treatment of solitary fibrous tumors localized in extremity, marginal resection together with radiotherapy may be an alternative treatment method for patients in low risk group according to risk stratification model, for whom wide resection is not possible. Wide resection is recommended in moderate and high risk groups to decrease local recurrence and metastasis risks.