Lontchi-Yimagou Eric, Mapa-Tassou Clarisse, Dehayem Mesmin Y, Essi Marie-José, Saji Jude, Takogue Remy, Sobngwi Eugène, Mbanya Jean Claude
Laboratory for Molecular Medicine and Metabolism, Biotechnology Center, The University of Yaoundé I, Yaoundé, Cameroon.
Department of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.
BMJ Open Diabetes Res Care. 2017 Jun 30;5(1):e000397. doi: 10.1136/bmjdrc-2017-000397. eCollection 2017.
To assess the effect of free diabetes care on metabolic control and on health-related quality of life (HRQoL) of youths living with type 1 diabetes in Cameroon.
We conducted a clinical audit of a multicenter prospective cohort, performed in three of the nine clinics of the 'Changing Diabetes in Children' (CDiC) project in Cameroon. We collected data on demography, glycemic control, diabetes acute complications, and patients' HRQoL at baseline and after 1 year of follow-up.
One hundred and four patients (51 female) were included. The mean age was 16±2 years (min-max: 9-18), the mean duration of diabetes was 5±3 years, and the mean HbA1C level was 11.4%±2.7%. A significant reduction in HbA1c (11.4%±2.7% vs 8.7±2.4%), episodes of severe hypoglycemia (27/104 vs 15/104), and episodes of ketoacidosis (31/104 vs 7/104) were observed after 1 year (p<0.05). We did not observe any significant difference in the total HRQoL score (p=0.66). However, we observed a significant decrease in diabetes-associated symptoms (p<0.05). Age, level of education, duration of diabetes, glycemic control, and the presence or absence of diabetes complications did not significantly affect the total HRQoL score.
One year after free diabetes care offered through the CDiC project, a significant improvement was observed in glycemic control and acute complications of diabetes, but not in the total score of HRQoL of youths living with type 1 diabetes enrolled in the project.
评估免费糖尿病护理对喀麦隆1型糖尿病青少年代谢控制及健康相关生活质量(HRQoL)的影响。
我们对喀麦隆“儿童糖尿病改变”(CDiC)项目九个诊所中的三个诊所进行的多中心前瞻性队列研究进行了临床审计。我们收集了基线时以及随访1年后的人口统计学、血糖控制、糖尿病急性并发症和患者HRQoL数据。
纳入了104例患者(51例女性)。平均年龄为16±2岁(最小 - 最大:9 - 18岁),糖尿病平均病程为5±3年,平均糖化血红蛋白(HbA1C)水平为11.4%±2.7%。1年后观察到糖化血红蛋白(11.4%±2.7%对8.7±2.4%)、严重低血糖发作次数(27/104对15/104)和酮症酸中毒发作次数(31/104对7/104)显著降低(p<0.05)。我们未观察到总HRQoL评分有任何显著差异(p = 0.66)。然而,我们观察到与糖尿病相关的症状有显著减少(p<0.05)。年龄、教育程度、糖尿病病程、血糖控制以及是否存在糖尿病并发症对总HRQoL评分无显著影响。
通过CDiC项目提供免费糖尿病护理1年后,在参与该项目的1型糖尿病青少年的血糖控制和糖尿病急性并发症方面观察到显著改善,但在其HRQoL总分方面未观察到改善。