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拇指色素沉着绒毛结节性滑膜炎——细胞诊断

Pigmented Villonodular Synovitis of Thumb-A Cytological Diagnosis.

作者信息

Bhatnagar Kaneeka, Bawa Akshdeep Singh, Narang Vikram, Kaur Pavneet

机构信息

Senior Resident, Department of Pathology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

Senior Resident, Department of Orthopedics, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

出版信息

J Clin Diagn Res. 2017 Jun;11(6):ED18-ED20. doi: 10.7860/JCDR/2017/28184.10099. Epub 2017 Jun 1.

Abstract

Pigmented Villonodular Synovitis (PVNS) is a unique benign proliferative process of unknown aetiology involving the synovial lined joints diffusely or focally. The entity remains a diagnostic challenge. This condition is attributed to an increased synovial proliferation causing villous or nodular changes of synovial lined joints leading to PVNS, Pigmented Villonodular Bursitis (PVNB) when arising from bursae or Pigmented Villonodular Tenosynovitis (PVNTS) originating from the tendon sheath. We present a case of a young female with nodular masses on right thumb with cytomorphological features on FNAC suggestive of PVNS which was finally confirmed by histopathology.

摘要

色素沉着绒毛结节性滑膜炎(PVNS)是一种病因不明的独特良性增殖性病变,可弥漫性或局灶性累及滑膜衬里的关节。该病变仍是一个诊断难题。这种情况归因于滑膜增生增加,导致滑膜衬里关节出现绒毛状或结节状改变,从而引发PVNS;当起源于滑囊时则导致色素沉着绒毛结节性滑囊炎(PVNB),起源于腱鞘时则导致色素沉着绒毛结节性腱鞘炎(PVNTS)。我们报告一例年轻女性,其右手拇指出现结节性肿块,细针穿刺抽吸活检(FNAC)的细胞形态学特征提示为PVNS,最终经组织病理学确诊。

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