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《养老院肺炎风险指数》:一种基于 MDS 的简单有效方法,用于确定 6 个月内肺炎和死亡的风险。

The Nursing Home Pneumonia Risk Index: A Simple, Valid MDS-Based Method of Identifying 6-Month Risk for Pneumonia and Mortality.

机构信息

Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC; Department of Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC; School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, NC.

出版信息

J Am Med Dir Assoc. 2017 Sep 1;18(9):810.e11-810.e14. doi: 10.1016/j.jamda.2017.06.008. Epub 2017 Jul 29.

Abstract

BACKGROUND

Pneumonia is the leading infectious cause of hospitalization and death for nursing home (NH) residents; however, diagnosis is often delayed because classic signs of infection are not present. We sought to identify NH residents at high risk for pneumonia, to identify persons to target for more intensive surveillance and preventive measures.

METHODS

Based on a literature review, we identified key risk factors for pneumonia and compiled them for use as prediction tool, limiting risk factors to those available on the Minimum Data Set (MDS). Next, we tested the tool's ability to predict 6-month pneumonia incidence and mortality rates in a sample of 674 residents from 7 NHs, evaluating it both as a continuous and a dichotomous variable, and applying both logistic regression and survival analysis to calculate estimates.

RESULTS

NH Pneumonia Risk Index scores ranged from -1 to 6, with a mean of 2.1, a median of 2, and a mode of 2. For the outcome of pneumonia, a 1-point increase in the index was associated with a risk odds ratio of 1.26 (P = .038) or a hazard ratio of 1.24 (P = .037); using it as a dichotomous variable (≤2 vs ≥3), the corresponding figures were a risk odds ratio of 1.78 (P = .045) and a hazard ratio of 1.82 (P = .025). For the outcome of mortality, a 1-point increase in the NH Pneumonia Risk Index was associated with a risk odds ratio of 1.58 (P = .002) and a hazard ratio of 1.45 (P = .013); using the index as a dichotomous variable, the corresponding figures were a risk odds ratio of 3.71 (P < .001) and a hazard ratio of 3.29 (P = .001).

CONCLUSIONS

The NH Pneumonia Risk Index can be used by NH staff to identify residents for whom to apply especially intensive preventive measures and surveillance. Because of its strong association with mortality, the index may also be valuable in care planning and discussion of advance directives.

摘要

背景

肺炎是导致养老院(NH)居民住院和死亡的主要感染原因;然而,由于没有出现典型的感染迹象,诊断往往会被延误。我们试图确定患有肺炎风险较高的 NH 居民,确定需要进行更密集监测和预防措施的人员。

方法

基于文献回顾,我们确定了肺炎的关键危险因素,并将其整理成预测工具,将危险因素限制在 MDS 上可用的范围内。接下来,我们在来自 7 个 NH 的 674 名居民的样本中测试了该工具预测 6 个月内肺炎发病率和死亡率的能力,将其作为连续变量和二分类变量进行评估,并应用逻辑回归和生存分析来计算估计值。

结果

NH 肺炎风险指数得分范围为-1 至 6,平均为 2.1,中位数为 2,模式为 2。对于肺炎的结果,指数增加 1 分与风险比为 1.26(P =.038)或风险比为 1.24(P =.037)相关;将其作为二分类变量(≤2 与≥3)使用时,相应的数字为风险比为 1.78(P =.045)和风险比为 1.82(P =.025)。对于死亡率的结果,NH 肺炎风险指数增加 1 分与风险比为 1.58(P =.002)和风险比为 1.45(P =.013)相关;将该指数作为二分类变量使用时,相应的数字为风险比为 3.71(P <.001)和风险比为 3.29(P =.001)。

结论

NH 工作人员可以使用 NH 肺炎风险指数识别需要特别密集预防措施和监测的居民。由于其与死亡率的强烈关联,该指数在护理计划和预先指示讨论中也可能具有价值。

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