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[主要表现为甲状旁腺功能亢进的多发性内分泌腺瘤病]

[Multiple endocrine adenomatosis manifested chiefly by hyperparathyroidism].

作者信息

Nachev S, Mikhaĭlov I, Donev S, Gruev I

出版信息

Vutr Boles. 1986;25(3):116-20.

PMID:2876552
Abstract

A case with multiple endocrine neoplasia was reported, including parathyroid adenoma, of the main cells of the gland, multiple small adenomas in the tail of pancreas, (cytologically and electron-microscopically determined as A cellular) and light-cellular adenoma of adrenal. The hyperfunction of parathyroid adenoma was manifested with hypercalcemia (3.75 mmol/l), and morphologically--with the multiple calcium metastases in lungs, kidneys and heart, established at necropsy. The cause for the death was the acutely advanced ischemic disease of myocardium, on the background of chronic pyelonephritis and renal insufficiency. The timely diagnosis of such morbid states is concluded to be important for the clinical practice and could lead to the saving of the patients by operative removal of the tumour.

摘要

报告了一例多发性内分泌肿瘤病例,包括甲状旁腺腺瘤(由腺主细胞构成)、胰腺尾部多个小腺瘤(经细胞学和电子显微镜检查确定为 A 细胞型)以及肾上腺透明细胞腺瘤。甲状旁腺腺瘤功能亢进表现为高钙血症(3.75 mmol/l),尸检发现形态学上存在肺部、肾脏和心脏的多处钙转移。死亡原因是在慢性肾盂肾炎和肾功能不全背景下急性进展的心肌缺血性疾病。得出结论,及时诊断此类病态对临床实践很重要,通过手术切除肿瘤可挽救患者生命。

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