Laptev B I, Afanas'ev S A, Prokop'eva V D, Antoshkin L V, Larionov N P
Biull Eksp Biol Med. 1986 Oct;102(10):389-90.
The effect of phenothiazines-trifluoroperazine frenolone, majeptile and aminazine on contractility of papillar muscle of Wistar male rats associated with short-term Ca-concentration increase up to 4 mM has been studied. There has been found the parameter-relaxation index-the change of which under the effect of phenothiazines (10(-5) M in all the cases) made use of significantly correlates with the constants, which reflect the similarity of given agents with calmodulin.
研究了吩噻嗪类药物——三氟拉嗪、氟哌利多、马耶普替尔和氯丙嗪对Wistar雄性大鼠乳头肌收缩性的影响，该影响与短期将钙浓度提高至4 mM有关。发现了参数——松弛指数，在所有情况下使用的吩噻嗪类药物（10⁻⁵ M）作用下其变化与反映给定药物与钙调蛋白相似性的常数显著相关。
