Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Pain. 2017 Nov;158(11):2189-2195. doi: 10.1097/j.pain.0000000000001023.
Pain catastrophizing is a significant risk factor for patients with knee osteoarthritis (KOA) and thus is a target for many psychological interventions for pain. This study examined if interventions targeting sleep found to be effective in improving sleep in KOA also reduce pain catastrophizing measured as a trait through the pain catastrophizing scale and measured as a daytime and nocturnal state through daily diaries. Secondary analyses were conducted on data collected as part of a randomized controlled trial assessing the effectiveness of cognitive behavioral therapy for insomnia in patients with KOA at 5 different time points: pretreatment, midtreatment and posttreatment and at 3- and 6-month follow-up. One hundred patients diagnosed with KOA and insomnia were randomized to receive either 8 sessions of cognitive behavioral therapy for insomnia or a placebo intervention of behavioral desensitization. Multilevel modeling revealed that both intervention groups showed a significant reduction pretreatment to posttreatment in all 3 measures of pain catastrophizing and maintained stable levels through the 6-month follow-up. Increased sleep continuity early in treatment (pretreatment to midtreatment), but not reductions in pain, was associated with a reduction in trait and nocturnal catastrophizing later in treatment (midtreatment to posttreatment). These results suggest that short interventions focusing on sleep can significantly reduce pain catastrophizing even in a clinical population with low baseline levels of catastrophizing, possibly through improving sleep continuity.
疼痛灾难化是膝骨关节炎(KOA)患者的一个重要风险因素,因此是许多针对疼痛的心理干预的目标。本研究考察了针对睡眠的干预措施是否能有效改善 KOA 患者的睡眠,同时通过疼痛灾难化量表衡量特质,通过日常日记衡量白天和夜间状态,从而降低疼痛灾难化。这是一项对随机对照试验数据进行的二次分析,评估认知行为疗法对 KOA 患者失眠的有效性,该试验在 5 个不同时间点收集数据:治疗前、治疗中、治疗后以及 3 个月和 6 个月随访。100 名被诊断为 KOA 和失眠的患者被随机分配接受 8 节认知行为疗法治疗失眠或行为脱敏的安慰剂干预。多层次模型显示,两个干预组在所有 3 项疼痛灾难化测量中均显示出治疗前至治疗后的显著降低,并在 6 个月的随访中保持稳定水平。治疗早期(治疗前至治疗中)的睡眠连续性增加,但疼痛减轻与治疗后期(治疗中至治疗后)特质和夜间灾难化的降低有关。这些结果表明,即使在基线灾难化水平较低的临床人群中,专注于睡眠的短期干预也可以显著降低疼痛灾难化,可能是通过改善睡眠连续性实现的。