Nassar C F, Haddad M E
Comp Biochem Physiol A Comp Physiol. 1986;85(2):229-32. doi: 10.1016/0300-9629(86)90243-4.
The unidirectional influx of calcium across rat liver slices is a carrier-mediated process which displays saturation kinetics. The presence of Mg2+ in the incubation medium competitively inhibits calcium influx into rat liver slices. Metabolic inhibitors such as ouabain and 2,4-dinitrophenol at a concentration of 1 X 10(-4) and 2.5 X 10(-4) M respectively, inhibited significantly (P less than 0.001) calcium influx across the liver slices. Calcium influx is dependent on the presence of sodium in the extracellular medium, and is significantly reduced (P less than 0.01) when sodium concentration in the preincubation solution is reduced to zero.
钙离子跨大鼠肝切片的单向内流是一个由载体介导的过程，呈现出饱和动力学。孵育介质中Mg2+的存在竞争性抑制钙离子流入大鼠肝切片。代谢抑制剂如哇巴因和2,4-二硝基苯酚，浓度分别为1×10(-4)和2.5×10(-4)M时，显著抑制（P<0.001）钙离子跨肝切片的内流。钙离子内流依赖于细胞外介质中钠离子的存在，当预孵育溶液中的钠离子浓度降至零时，钙离子内流显著减少（P<0.01）。
