Li L, Luther M, Macklin K, Pugh D, Li J, Zhang J, Roberts J, Kaltenboeck B, Wang C
Thompson Bishop Sparks State Diagnostic Laboratory,Auburn, AL,USA.
Department of Poultry Science,College of Agriculture, Auburn University,AL,USA.
Epidemiol Infect. 2017 Oct;145(13):2701-2703. doi: 10.1017/S0950268817001650. Epub 2017 Aug 3.
Chlamydia gallinacea, a new chlamydial agent, has been reported in four European countries as well as Argentina and China. Experimentally infected chickens with C. gallinacea in previous study showed no clinical signs but had significantly reduced gains in body weight (6·5-11·4%). Slaughterhouse workers exposed to infected chickens have developed atypical pneumonia, indicating C. gallinacea is likely a zoonotic agent. In this study, FRET-PCR confirmed that C. gallinacea was present in 12·4% (66/531) of oral-pharyngeal samples from Alabama backyard poultry. Phylogenetic comparisons based on ompA variable domain showed that 16 sequenced samples represented 14 biotypes. We report for the first time the presence of C. gallinacea in North America, and this warrants further research on the organism's pathogenicity, hosts, transmission, and zoonotic potential.
鸡衣原体是一种新的衣原体病原体，已在四个欧洲国家以及阿根廷和中国被报道。在先前的研究中，用鸡衣原体实验性感染鸡，结果显示鸡没有临床症状，但体重显著减轻（6.5%-11.4%）。接触感染鸡的屠宰场工人患上了非典型肺炎，这表明鸡衣原体可能是人畜共患病原体。在本研究中，荧光共振能量转移聚合酶链反应（FRET-PCR）证实，来自阿拉巴马州后院家禽的口咽样本中有12.4%（66/531）存在鸡衣原体。基于ompA可变区的系统发育比较表明，16个测序样本代表14种生物型。我们首次报告了北美存在鸡衣原体，这值得对该病原体的致病性、宿主、传播和人畜共患病潜力进行进一步研究。
